SCHEMBL15088985

SCHEMBL15088985

CC1(C)c2ccccc2-c2cc3c(cc21)N(c1ccccc1)c1cccc2cccc-3c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.41
PGR P06401 10/20 0.41
ALDH1A1 P00352 5/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
HSD17B10 Q99714 4/20 0.32
HPGD P15428 3/20 0.32
KDM4E B2RXH2 3/20 0.32
MAPT P10636 3/20 0.32
GAA P10253 2/20 0.32
NSD2 O96028 1/20 0.32
APP P05067 1/20 0.32
SNCA P37840 1/20 0.32
TYMS P04818 1/20 0.32
MAPK1 P28482 3/20 0.32
CASP1 P29466 2/20 0.32
CASP7 P55210 2/20 0.32
TSHR P16473 2/20 0.32
TP53 P04637 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15088990 0.93 PDE6D (0.52) PDE6DPGRALDH1A1MEN1KMT2A
SCHEMBL15088980 0.92 PDE6D (0.43) PDE6DPGRALDH1A1MEN1KMT2A
SCHEMBL15088979 0.91 ALDH1A1 (0.41) PDE6DPGRALDH1A1MEN1KMT2A
SCHEMBL15089088 0.90 PDE6D (0.43) PDE6DPGRMEN1KMT2A
SCHEMBL15089064 0.89 PDE6D (0.39) PDE6DPGR
SCHEMBL15089007 0.88 HSD17B10 (0.44) PDE6DPGRALDH1A1HSD17B10HPGD
SCHEMBL15088992 0.87 PDE6D (0.36) PDE6DPGRMEN1KMT2AKDM4E
SCHEMBL15088991 0.86 PGR (0.33) PDE6DPGRMEN1KMT2AKDM4E
SCHEMBL15089001 0.84 PDE6D (0.37) PDE6DALDH1A1HSD17B10HPGDKDM4E
SCHEMBL15089000 0.83 PDE6D (0.36) PDE6DALDH1A1MEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed