SCHEMBL15089124

SCHEMBL15089124

c1ccc(-n2c3ccccc3c3cc4c(cc32)N(c2ncccn2)c2cccc3cccc-4c23)cc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PDE6D O43924 1/20 0.35
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
PSMD14 O00487 1/20 0.31
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.31
MMP2 P08253 1/20 0.31
HTR1A P08908 1/20 0.30
DRD2 P14416 1/20 0.30
HTR2A P28223 1/20 0.30
HTR7 P34969 1/20 0.30
HTR6 P50406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15088907 0.92 ALDH1A1 (0.34) KDM4EL3MBTL1PDE6DALDH1A1GAA
SCHEMBL15089137 0.89 PDE6D (0.42) KDM4EPDE6DALDH1A1GAA
SCHEMBL15089115 0.89 KDM4E (0.43) KDM4EATML3MBTL1PDE6DALDH1A1
SCHEMBL15089133 0.89 PDE6D (0.35) KDM4EATML3MBTL1PDE6D
SCHEMBL15088905 0.88 L3MBTL1 (0.46) KDM4EATML3MBTL1PDE6DALDH1A1
SCHEMBL15089127 0.87 L3MBTL1 (0.45) KDM4EATML3MBTL1PDE6DALDH1A1
SCHEMBL15089118 0.87 PDE6D (0.39) KDM4EATML3MBTL1PDE6DALDH1A1
SCHEMBL15089256 0.87 PDE6D (0.38) KDM4EPDE6DALDH1A1HTR6
SCHEMBL15089151 0.87 KDM4E (0.40) KDM4EATML3MBTL1PDE6DALDH1A1
SCHEMBL15089112 0.86 L3MBTL1 (0.44) KDM4EATML3MBTL1PDE6DALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed