SCHEMBL15089240

SCHEMBL15089240

c1ccc(-c2ccc3c(c2)c2cc4c(cc2n3-c2ccccn2)N(c2ccc(-c3cccnc3)cn2)c2cccc3cccc-4c23)nc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.36
CYP2A6 P11509 2/20 0.35
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
GRM5 P41594 1/20 0.33
IRAK4 Q9NWZ3 1/20 0.33
VHL P40337 1/20 0.32
PDE6D O43924 1/20 0.31
CNR2 P34972 1/20 0.31
HRH1 P35367 1/20 0.31
HTR6 P50406 1/20 0.31
NPC1 O15118 1/20 0.31
TP53 P04637 1/20 0.31
PKM P14618 1/20 0.31
TSHR P16473 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP17A1 P05093 1/20 0.30
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089072 0.98 MAPT (0.37) MAPTCYP2A6KDM4EALDH1A1GAA
SCHEMBL15089157 0.93 PDE6D (0.36) MAPTCYP2A6KDM4EALDH1A1GAA
SCHEMBL15089243 0.93 KDM4E (0.40) MAPTKDM4EALDH1A1GAAIRAK4
SCHEMBL15089140 0.92 KDM4E (0.36) MAPTCYP2A6KDM4EALDH1A1GAA
SCHEMBL15089060 0.92 MAPT (0.39) MAPTKDM4EALDH1A1GAAIRAK4
SCHEMBL15089160 0.91 PDE6D (0.39) MAPTKDM4EALDH1A1GAAIRAK4
SCHEMBL15089148 0.90 CYP2A6 (0.37) MAPTCYP2A6GRM5VHLCNR2
SCHEMBL15089268 0.90 PDE6D (0.36) MAPTCYP2A6ALDH1A1PDE6DHRH1
SCHEMBL15089267 0.89 PDE6D (0.38) MAPTKDM4EALDH1A1GAAIRAK4
SCHEMBL15089135 0.88 KDM4E (0.40) MAPTKDM4EALDH1A1GAAIRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed