SCHEMBL15089072

SCHEMBL15089072

c1ccc(-c2ccc3c(c2)c2cc4c(cc2n3-c2ccc(-c3cccnc3)cn2)N(c2ccc(-c3cccnc3)cn2)c2cccc3cccc-4c23)nc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.37
CYP2A6 P11509 2/20 0.37
GRM5 P41594 1/20 0.33
CNR2 P34972 1/20 0.32
IRAK4 Q9NWZ3 1/20 0.32
NPC1 O15118 1/20 0.31
TP53 P04637 1/20 0.31
PKM P14618 1/20 0.31
TSHR P16473 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HRH1 P35367 1/20 0.31
HTR6 P50406 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
CYP11B1 P15538 2/20 0.31
CYP17A1 P05093 1/20 0.31
CYP19A1 P11511 1/20 0.31
CYP11B2 P19099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089240 0.98 MAPT (0.36) MAPTCYP2A6GRM5CNR2IRAK4
SCHEMBL15089060 0.93 MAPT (0.39) MAPTCNR2IRAK4KDM4EALDH1A1
SCHEMBL15089157 0.92 PDE6D (0.36) MAPTCYP2A6IRAK4HRH1HTR6
SCHEMBL15089148 0.92 CYP2A6 (0.37) MAPTCYP2A6GRM5CNR2HRH1
SCHEMBL15089268 0.91 PDE6D (0.36) MAPTCYP2A6HRH1HTR6ALDH1A1
SCHEMBL15089243 0.91 KDM4E (0.40) MAPTCNR2IRAK4NPC1TSHR
SCHEMBL15089267 0.91 PDE6D (0.38) MAPTCNR2IRAK4KDM4EALDH1A1
SCHEMBL15089140 0.90 KDM4E (0.36) MAPTCYP2A6TSHRRAB9ASMN1; SMN2
SCHEMBL15088899 0.89 CYP11B1 (0.36) MAPTCYP2A6TSHRRAB9ASMN1; SMN2
SCHEMBL15089160 0.89 PDE6D (0.39) MAPTCNR2IRAK4TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed