SCHEMBL15089148

SCHEMBL15089148

c1ccc(-c2ccc3c(c2)c2cc4c(cc2n3-c2ccc(-c3cccnc3)cn2)N(c2ccc(-c3cccnc3)cn2)c2cccc3c(-c5ccccn5)ccc-4c23)nc1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.37
MAPT P10636 1/20 0.35
CNR2 P34972 1/20 0.34
GRM5 P41594 2/20 0.33
VHL P40337 1/20 0.32
HRH1 P35367 1/20 0.31
HTR6 P50406 1/20 0.31
PIM1 P11309 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
MAPK14 Q16539 1/20 0.31
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30
G6PD P11413 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30
SCN5A Q14524 1/20 0.30
SCN9A Q15858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089172 0.93 CNR2 (0.39) MAPTCNR2MAPK14
SCHEMBL15089072 0.92 MAPT (0.37) CYP2A6MAPTCNR2GRM5HRH1
SCHEMBL15089240 0.90 MAPT (0.36) CYP2A6MAPTCNR2GRM5VHL
SCHEMBL15088895 0.88 CYP2A6 (0.35) CYP2A6MAPTGRM5VHLPIM1
SCHEMBL15088834 0.88 PIK3CA (0.37) MAPTVHLHRH1HTR6MAPK14
SCHEMBL15089178 0.87 MAPK14 (0.33) MAPTCNR2PIM1MAPK14
SCHEMBL15088822 0.87 CNR2 (0.38) MAPTCNR2MAPK14
SCHEMBL15089210 0.87 MEN1 (0.37) MAPTCNR2MAPK14
SCHEMBL15088917 0.85 CYP19A1 (0.34) GRM5
SCHEMBL15089171 0.84 COMT (0.33) CNR2MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed