SCHEMBL15089356

SCHEMBL15089356

Cc1ccnc(N2c3cc4c(cc3-c3cccc5cccc2c35)c2cc(-c3ccncc3)ccc2n4-c2ccccc2)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.34
ALDH1A1 P00352 4/20 0.34
LMNA P02545 3/20 0.34
MAPT P10636 3/20 0.34
KDM4E B2RXH2 2/20 0.34
GLA P06280 1/20 0.34
PIK3CA P42336 2/20 0.33
PDE10A Q9Y233 2/20 0.33
PIK3CD O00329 1/20 0.33
PIK3CB P42338 1/20 0.33
MTOR P42345 1/20 0.33
PIK3CG P48736 1/20 0.33
KCNH2 Q12809 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
DPP4 P27487 1/20 0.33
S1PR4 O95977 1/20 0.33
GAA P10253 1/20 0.33
PABPC1 P11940 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089204 0.96 PDE6D (0.38) PDE6DALDH1A1LMNAMAPTKDM4E
SCHEMBL15089294 0.90 ALDH1A1 (0.39) PDE6DALDH1A1LMNAMAPTKDM4E
SCHEMBL15089168 0.90 PDE6D (0.41) PDE6DALDH1A1KDM4EPIK3CAGAA
SCHEMBL15089116 0.88 SMN1; SMN2 (0.38) PDE6DALDH1A1LMNAMAPTKDM4E
SCHEMBL15089256 0.86 PDE6D (0.38) PDE6DALDH1A1MAPTKDM4EPIK3CA
SCHEMBL15089139 0.85 PDE6D (0.38) PDE6DALDH1A1LMNAKDM4EMEN1
SCHEMBL15089136 0.85 PDE6D (0.43) PDE6DALDH1A1LMNAMAPTKDM4E
SCHEMBL15089357 0.84 PDE6D (0.36) PDE6DALDH1A1KDM4EGAA
SCHEMBL15089143 0.84 PDE6D (0.45) PDE6DALDH1A1MAPTKDM4EPIK3CA
SCHEMBL15089286 0.84 PDE6D (0.40) PDE6DALDH1A1KDM4EPIK3CAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed