SCHEMBL15089116

SCHEMBL15089116

Cc1ccnc(N2c3cc4c(cc3-c3cccc5cccc2c35)c2ccccc2n4-c2ccccc2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 3/20 0.38
MAPT P10636 2/20 0.38
RAB9A P51151 2/20 0.38
GAA P10253 2/20 0.38
MEN1 O00255 1/20 0.38
S1PR4 O95977 1/20 0.38
PABPC1 P11940 1/20 0.38
S1PR1 P21453 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 3/20 0.36
GLA P06280 1/20 0.36
DPP4 P27487 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ATM Q13315 1/20 0.35
PDE10A Q9Y233 2/20 0.34
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15088896 0.93 SMN1; SMN2 (0.40) SMN1; SMN2LMNAMAPTRAB9AGAA
SCHEMBL15089204 0.91 PDE6D (0.38) SMN1; SMN2LMNAMAPTRAB9AGAA
SCHEMBL15089356 0.88 PDE6D (0.34) SMN1; SMN2LMNAMAPTRAB9AGAA
SCHEMBL15089139 0.88 PDE6D (0.38) LMNAGAAMEN1KMT2AALDH1A1
SCHEMBL15089115 0.88 KDM4E (0.43) SMN1; SMN2LMNAMAPTGAAMEN1
SCHEMBL15088807 0.86 L3MBTL1 (0.40) SMN1; SMN2LMNAMAPTGAAMEN1
SCHEMBL15089111 0.85 KDM4E (0.33) LMNAGAAMEN1KMT2AALDH1A1
SCHEMBL15089294 0.85 ALDH1A1 (0.39) SMN1; SMN2LMNAMAPTRAB9AGAA
SCHEMBL15089124 0.83 KDM4E (0.40) GAAALDH1A1KDM4EL3MBTL1ATM
SCHEMBL15088810 0.83 L3MBTL1 (0.40) MAPTMEN1KMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed