Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTPRB | P23467 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7233451 | 0.85 | PTPRB (0.45) | PTPRBALDH1A1LMNAMAPK1RECQL | |
| SCHEMBL2925457 | 0.85 | PTPRB (0.42) | KMT2APTPRBALDH1A1RECQLMAPT | |
| SCHEMBL2490507 | 0.85 | ABCB11 (0.49) | KMT2AL3MBTL1GAAPTPRBALDH1A1 | |
| SCHEMBL27159469 | 0.82 | MAPT (0.45) | KMT2AL3MBTL1GAAALDH1A1LMNA | |
| SCHEMBL27159467 | 0.82 | MAPT (0.45) | KMT2AL3MBTL1GAAALDH1A1LMNA | |
| SCHEMBL1111262 | 0.80 | PTPRB (0.39) | KMT2APTPRBALDH1A1RECQLMAPT | |
| SCHEMBL1508958 | 0.79 | GAA (0.42) | KMT2AL3MBTL1GAAPTPRBALDH1A1 | |
| SCHEMBL28553767 | 0.78 | CA1 (0.46) | KMT2AL3MBTL1GAAALDH1A1LMNA | |
| SCHEMBL10728032 | 0.78 | ALDH1A1 (0.45) | KMT2AL3MBTL1GAAGLAALDH1A1 | |
| SCHEMBL838832 | 0.76 | KMT2A (0.51) | KMT2AL3MBTL1GAAGLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298778-A1 | IMIDAZOTHIAZOLE DERIVATIVE HAVING 4,7-DIAZASPIROÝ2.5¨OCTANE RING STRUCTURE | Daiichi Sankyo Company, Limited (JP) | 2011-03-23 | — | — | EP | disclosed |