SCHEMBL15093993

SCHEMBL15093993

CC(=O)OO[Si](C)(C)C(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.30
TSHR P16473 1/20 0.30
PREP P48147 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29182294 0.78 GAA (0.31) GAA
SCHEMBL8056622 0.78
SCHEMBL7749027 0.75
SCHEMBL31537920 0.75 ALDH1A1 (0.31) ALDH1A1
SCHEMBL475925 0.74 ALDH1A1 (0.33) ALDH1A1TSHRPREPGAA
SCHEMBL28842043 0.73 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL9522115 0.73
SCHEMBL31386976 0.72 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL28586961 0.72 ADRB2 (0.32)
SCHEMBL9794154 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2800750-B1 CARBOCYCLIC NUCLEOSIDES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS CELLCEUTIX CORP (US) 2016-11-23 EP disclosed
US-8895569-B2 Carbocyclic nucleosides and their pharmaceutical use and compositions CELLCEUTIX CORPORATION (US) 2014-11-25 US disclosed
EP-2800750-A1 CARBOCYCLIC NUCLEOSIDES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS Cellceutix Corporation (US) 2014-11-12 EP disclosed
WO-2013103601-A1 CARBOCYCLIC NUCLEOSIDES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS CELLCEUTIX CORPORATION (US) 2013-07-11 WO disclosed