SCHEMBL15094064

SCHEMBL15094064

O=C(O)CCC(=O)c1ccc(C(=O)Cl)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR4A2 P43354 1/20 0.65
▸ KMT2A Q03164 1/20 0.64
▸ CYP1A2 P05177 3/20 0.62
▸ LMNA P02545 2/20 0.62
▸ FFAR1 O14842 1/20 0.62
▸ RAB9A P51151 1/20 0.62
▸ SMN1; SMN2 Q16637 1/20 0.62
▸ HIF1A Q16665 1/20 0.62
▸ ALDH1A1 P00352 3/20 0.59
▸ CYP2C19 P33261 2/20 0.59
▸ GAA P10253 1/20 0.59
▸ USP5 P45974 1/20 0.58
▸ L3MBTL1 Q9Y468 2/20 0.56
▸ MMP2 P08253 2/20 0.53
▸ MMP12 P39900 2/20 0.53
▸ HDAC3 O15379 1/20 0.48
▸ HDAC4 P56524 1/20 0.48
▸ HDAC1 Q13547 1/20 0.48
▸ HDAC7 Q8WUI4 1/20 0.48
▸ HDAC2 Q92769 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10353454 0.89 NR4A2 (0.81) NR4A2KMT2ACYP1A2LMNAFFAR1
SCHEMBL4476891 0.87 NR4A2 (0.65) NR4A2KMT2ACYP1A2LMNAFFAR1
SCHEMBL15093932 0.83 NR4A2 (0.54) NR4A2KMT2ACYP1A2LMNAFFAR1
SCHEMBL392858 0.83 NR4A2 (0.65) NR4A2KMT2ACYP1A2LMNAFFAR1
SCHEMBL8206307 0.82 NR4A2 (0.71) NR4A2KMT2ACYP1A2LMNAFFAR1
SCHEMBL10884944 0.82 SMN1; SMN2 (0.88) NR4A2KMT2ACYP1A2LMNAFFAR1
SCHEMBL2632218 0.80 RAB9A (0.68) NR4A2KMT2ACYP1A2LMNAFFAR1
SCHEMBL354105 0.79 NR4A2 (1.00) NR4A2KMT2ACYP1A2LMNAFFAR1
SCHEMBL9352918 0.79 L3MBTL1 (0.62) NR4A2KMT2ACYP1A2LMNAFFAR1
SCHEMBL2652443 0.78 NR4A2 (0.65) NR4A2KMT2ACYP1A2LMNAFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106232214-B Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2021-01-15 — — CN disclosed
EP-2776146-B1 METHOD OF PREPARATION OF A COMPOSITE POLYAMIDE MEMBRANE DDP SPECIALTY ELECTRONIC MAT US INC (US) 2020-05-13 — — EP disclosed
EP-3092061-B1 COMPOSITE POLYAMIDE MEMBRANE HAVING HIGH ACID CONTENT AND LOW AZO CONTENT DOW GLOBAL TECHNOLOGIES LLC (US) 2020-02-05 — — EP disclosed
CN-105848758-B Separation of hydrocarbons from aqueous mixtures using fouling resistant reverse osmosis membranes 陶氏环球技术有限责任公司 2020-01-17 — — CN disclosed
CN-105873666-B Composite polyamide membrane with high acid content and low azo content DOW GLOBAL TECHNOLOGIES LLC (US) 2019-11-01 — — CN disclosed
CN-106457160-B Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2019-10-08 — — CN disclosed
CN-105848759-B Desalting an aqueous mixture containing nanosized particles using a fouling resistant reverse osmosis membrane 陶氏环球技术有限责任公司 2019-04-02 — — CN disclosed
CN-106170333-B Composite polyamide membrane treated with dihydroxyaryl compound and nitrous acid 陶氏环球技术有限责任公司 2019-02-15 — — CN disclosed
CN-105873665-B Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2019-01-01 — — CN disclosed
US-10137418-B2 Composite polyamide membrane made via interfacial polymerization using a blend of non-polar solvents DOW GLOBAL TECHNOLOGIES LLC (US) 2018-11-27 — — US disclosed
US-20150306548-A1 COMPOSITE POLYAMIDE MEMBRANE MADE VIA INTERFACIAL POLYMERIZATION USING A BLEND OF NON-POLAR SOLVENTS DOW GLOBAL TECHNOLOGIES LLC 2015-10-29 — — US disclosed
CN-104918687-A Composite polyamide membranes made via interfacial polymerization using blends of non-polar solvents DOW GLOBAL TECHNOLOGIES LLC 2015-09-16 — — CN disclosed
US-9073015-B2 Composite polyamide membrane DOW GLOBAL TECHNOLOGIES LLC (US) 2015-07-07 — — US disclosed
US-20140370191-A1 COMPOSITE POLYAMIDE MEMBRANE DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-18 — — US disclosed
EP-2776146-A1 COMPOSITE POLYAMIDE MEMBRANE Dow Global Technologies LLC (US) 2014-09-17 — — EP disclosed
CN-104039429-A Composite polyamide membrane DOW GLOBAL TECHNOLOGIES INC 2014-09-10 — — CN disclosed
US-20140199483-A1 COMPOSITE POLYAMIDE MEMBRANE INCLUDING TRI-HYDROCARBYL PHOSPHATE DOW GLOBAL TECHNOLOGIES LLC (US) 2014-07-17 — — US disclosed
WO-2014109945-A1 COMPOSITE POLYAMIDE MEMBRANE INCLUDING TRI-HYDROCARBYL PHOSPHATE DOW GLOBAL TECHNOLOGIES LLC (US) 2014-07-17 — — WO disclosed
WO-2014109946-A1 COMPOSITE POLYAMIDE MEMBRANE DOW GLOBAL TECHNOLOGIES LLC (US) 2014-07-17 — — WO disclosed
WO-2013103666-A1 COMPOSITE POLYAMIDE MEMBRANE DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-11 — — WO disclosed
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