SCHEMBL15094641

SCHEMBL15094641

O=C(OC(C(F)(F)F)C(F)(F)F)C1CNCCN1Cc1ccc(C(F)(F)F)cc1N1CCCC1

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 14/20 0.58
ABHD6 Q9BV23 14/20 0.58
CYP2D6 P10635 1/20 0.58
PLA2G7 Q13093 9/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19974451 0.90 MGLL (0.53) MGLLABHD6CYP2D6PLA2G7
SCHEMBL15094777 0.89 MGLL (0.58) MGLLABHD6CYP2D6PLA2G7
SCHEMBL15094565 0.89 MGLL (0.58) MGLLABHD6CYP2D6PLA2G7
SCHEMBL15094702 0.88 MGLL (0.58) MGLLABHD6CYP2D6PLA2G7
SCHEMBL15094506 0.87 MGLL (0.56) MGLLABHD6CYP2D6PLA2G7
SCHEMBL15094728 0.84 MGLL (0.49) MGLLABHD6CYP2D6PLA2G7
SCHEMBL19974302 0.83 MGLL (0.44) MGLLABHD6CYP2D6PLA2G7
SCHEMBL15094590 0.83 ABHD6 (0.42) MGLLABHD6CYP2D6PLA2G7
SCHEMBL15094582 0.83 ABHD6 (0.41) MGLLABHD6CYP2D6PLA2G7
SCHEMBL15094555 0.81 ABHD6 (0.49) MGLLABHD6CYP2D6PLA2G7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2800565-A1 CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME Abide Therapeutics, Inc. (US) 2014-11-12 EP disclosed
WO-2013103973-A1 CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME ABIDE THERAPEUTICS (US) 2013-07-11 WO disclosed