Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15094568 | 0.85 | HCAR2 (0.39) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL15266847 | 0.85 | RXFP1 (0.40) | HDAC4HTR2AHTR2CHTR2BADRB1 | |
| SCHEMBL15094649 | 0.84 | HTR2A (0.40) | HTR2AHTR2CHTR2BSIGMAR1LMNA | |
| SCHEMBL18284816 | 0.82 | SIGMAR1 (0.39) | OPRM1OPRD1HTR2AHTR2CHTR2B | |
| SCHEMBL15266756 | 0.82 | HTR6 (0.37) | HTR2AHTR2CHTR2BADRB1SIGMAR1 | |
| SCHEMBL15266762 | 0.82 | HDAC4 (0.39) | HDAC4HTR2AHTR2CHTR2BLMNA | |
| SCHEMBL15094651 | 0.81 | SLC6A2 (0.43) | LMNAHSD17B10KCNH2 | |
| SCHEMBL15266268 | 0.80 | TSHR (0.43) | SIGMAR1LMNA | |
| SCHEMBL15266744 | 0.80 | SLC6A2 (0.39) | HTR2AHTR2CHTR2BKCNH2 | |
| SCHEMBL15266771 | 0.77 | GAA (0.46) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828253-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2015-01-28 | — | — | EP | claimed |
| EP-2800565-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2014-11-12 | — | — | EP | claimed |
| WO-2013142307-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | ABIDE THERAPEUTICS (US) | 2013-09-26 | — | — | WO | claimed |
| WO-2013103973-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | ABIDE THERAPEUTICS (US) | 2013-07-11 | — | — | WO | claimed |