Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15095085 | 0.88 | FPR2 (0.30) | FPR2 | |
| SCHEMBL15197279 | 0.83 | FPR2 (0.39) | FPR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2498914 | 0.82 | FPR2 (0.44) | FPR2KDM4EALDH1A1 | |
| SCHEMBL15095084 | 0.80 | FPR2 (0.33) | FPR2 | |
| SCHEMBL4235144 | 0.80 | SMN1; SMN2 (0.37) | FPR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1740513 | 0.74 | FPR2 (0.35) | FPR2KDM4EALDH1A1POLB | |
| SCHEMBL4963238 | 0.72 | SMN1; SMN2 (0.40) | FPR2KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL1740516 | 0.71 | FPR2 (0.33) | FPR2 | |
| SCHEMBL24574386 | 0.70 | GRIN2B (0.39) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL17049815 | 0.69 | KMT2A (0.43) | KDM4EALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422251-B2 | Metal complexes of poly(carboxyl)amine-containing ligands having an affinity for carbonic anhydrase IX | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-9422251-B2 | Metal complexes of poly(carboxyl)amine-containing ligands having an affinity for carbonic anhydrase IX | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-20160009664-A1 | METAL COMPLEXES OF POLY(CARBOXYL)AMINE-CONTAINING LIGANDS HAVING AN AFFINITY FOR CARBONIC ANHYDRASE IX | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2016-01-14 | — | — | US | disclosed |
| US-20160009664-A1 | METAL COMPLEXES OF POLY(CARBOXYL)AMINE-CONTAINING LIGANDS HAVING AN AFFINITY FOR CARBONIC ANHYDRASE IX | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2016-01-14 | — | — | US | disclosed |
| US-9120837-B2 | Metal complexes of poly(carboxyl)amine-containing ligands having an affinity for carbonic anhydrase IX | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2015-09-01 | — | — | US | disclosed |
| US-9120837-B2 | Metal complexes of poly(carboxyl)amine-containing ligands having an affinity for carbonic anhydrase IX | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2015-09-01 | — | — | US | disclosed |
| EP-2800471-A1 | METAL COMPLEXES OF POLY(CARBOXYL)AMINE-CONTAINING LIGANDS HAVING AN AFFINITY FOR CARBONIC ANHYDRASE IX | Molecular Insight Pharmaceuticals (US) | 2014-11-12 | — | — | EP | disclosed |
| US-20130216477-A1 | METAL COMPLEXES OF POLY(CARBOXYL)AMINE-CONTAINING LIGANDS HAVING AN AFFINITY FOR CARBONIC ANHYDRASE IX | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2013-08-22 | — | — | US | disclosed |
| US-20130216477-A1 | METAL COMPLEXES OF POLY(CARBOXYL)AMINE-CONTAINING LIGANDS HAVING AN AFFINITY FOR CARBONIC ANHYDRASE IX | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2013-08-22 | — | — | US | disclosed |
| WO-2013103813-A1 | METAL COMPLEXES OF POLY(CARBOXYL)AMINE-CONTAINING LIGANDS HAVING AN AFFINITY FOR CARBONIC ANHYDRASE IX | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2013-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009664-A1 | METAL COMPLEXES OF POLY(CARBOXYL)AMINE-CONTAINING LIGANDS HAVING AN AFFINITY FOR CARBONIC ANHYDRASE IX | CA9, CA4, CA7 | FPR2 4289/4885KDM4E 307/4885ALDH1A1 1768/4885 |
| US-20130216477-A1 | METAL COMPLEXES OF POLY(CARBOXYL)AMINE-CONTAINING LIGANDS HAVING AN AFFINITY FOR CARBONIC ANHYDRASE IX | CA9, CA4, CA7 | FPR2 4307/4885KDM4E 284/4885ALDH1A1 1738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.