SCHEMBL15095085

SCHEMBL15095085

CC(C)(C)OC(=O)CCC(CCC(=O)O)(CC(C(=O)O)(C(C)(C)C)C(C)(C)C)NC(=O)Cn1ccnc1C=O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15095083 0.88 FPR2 (0.35) FPR2
SCHEMBL15095084 0.79 FPR2 (0.33) FPR2
SCHEMBL2498914 0.73 FPR2 (0.44) FPR2
SCHEMBL15197279 0.72 FPR2 (0.39) FPR2
SCHEMBL4235144 0.71 SMN1; SMN2 (0.37) FPR2
SCHEMBL17049815 0.68 KMT2A (0.43)
SCHEMBL1740516 0.68 FPR2 (0.33) FPR2
SCHEMBL1740513 0.67 FPR2 (0.35) FPR2
SCHEMBL16580126 0.66 ALPG (0.43) FPR2
SCHEMBL4963238 0.65 SMN1; SMN2 (0.40) FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2800471-A1 METAL COMPLEXES OF POLY(CARBOXYL)AMINE-CONTAINING LIGANDS HAVING AN AFFINITY FOR CARBONIC ANHYDRASE IX Molecular Insight Pharmaceuticals (US) 2014-11-12 EP disclosed
WO-2013103813-A1 METAL COMPLEXES OF POLY(CARBOXYL)AMINE-CONTAINING LIGANDS HAVING AN AFFINITY FOR CARBONIC ANHYDRASE IX MOLECULAR INSIGHT PHARMACEUTICALS (US) 2013-07-11 WO disclosed