SCHEMBL15095089

SCHEMBL15095089

CC[Si](CC)(CC)OCC1CO1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.43
ALDH1A1 P00352 10/20 0.43
TDP1 Q9NUW8 3/20 0.41
TSHR P16473 5/20 0.40
MAPK1 P28482 1/20 0.40
GLA P06280 1/20 0.34
TP53 P04637 4/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
HIF1A Q16665 2/20 0.32
CYP3A4 P08684 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARG P37231 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9971103 1.00 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL11659742 0.77 ALDH1A1 (0.48) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL812694 0.77
SCHEMBL647425 0.77 ALDH1A1 (0.48) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL10900694 0.76 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL23521486 0.76 SMN1; SMN2 (0.44) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL3856312 0.74 SMN1; SMN2 (0.42) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL8622001 0.74 SMN1; SMN2 (0.42) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL2783666 0.74 TSHR (0.46) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL752412 0.73 TSHR (0.46) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112930419-B Surface treatment solution composition and method for producing hot dip galvanized steel sheet surface-treated with the same 浦项股份有限公司 2023-06-09 CN claimed
CN-112930419-B Surface treatment solution composition and method for producing hot dip galvanized steel sheet surface-treated with the same 浦项股份有限公司 2023-06-09 CN disclosed
US-8481772-B2 Trihydroxy polyunsaturated eicosanoid derivatives UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2013-07-09 US disclosed