Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.77 |
| ▸ | MAPT | P10636 | 8/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.75 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.75 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
| ▸ | DHODH | Q02127 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068265 | 0.94 | MEN1 (0.85) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL19049494 | 0.92 | MEN1 (0.66) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL7945104 | 0.92 | MEN1 (0.66) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL10890390 | 0.91 | KMT2A (0.65) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL10890387 | 0.91 | KMT2A (0.65) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL11824063 | 0.91 | MEN1 (0.70) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL11824071 | 0.91 | MEN1 (0.70) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL11547023 | 0.91 | KMT2A (0.65) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL19084372 | 0.91 | MEN1 (0.64) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL435677 | 0.87 | KMT2A (0.74) | MEN1KMT2AMAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063648-A | Solid catalyst component for propylene polymerization and propylene polymerization catalyst system | 中国石油天然气股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-3750885-A1 | COMPOUND HAVING BET INHIBITORY ACTIVITY AND PREPARATION METHOD AND USE THEREFOR | Shanghai Haihe Pharmaceutical Co., Ltd. (CN) | 2020-12-16 | — | — | EP | disclosed |
| CN-111683932-A | Compound with BET inhibition activity, preparation method and application thereof | 上海海和药物研究开发有限公司 | 2020-09-18 | — | — | CN | disclosed |
| WO-2019154329-A1 | COMPOUND HAVING BET INHIBITORY ACTIVITY AND PREPARATION METHOD AND USE THEREFOR | 上海海和药物研究开发有限公司 | 2019-08-15 | — | — | WO | disclosed |
| US-8481775-B2 | Method for improving the color index of organopolysiloxanes | DSM IP ASSETS B.V. (NL) | 2013-07-09 | — | — | US | disclosed |