SCHEMBL435677

SCHEMBL435677

CCOC(=O)C(=Cc1ccc(O)cc1)C(=O)OCC

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.74
MEN1 O00255 7/20 0.74
MAPT P10636 7/20 0.73
LMNA P02545 3/20 0.73
NPSR1 Q6W5P4 2/20 0.73
CYP1A2 P05177 1/20 0.73
CYP2C9 P11712 1/20 0.73
CYP2C19 P33261 1/20 0.73
S1PR4 O95977 1/20 0.73
S1PR1 P21453 1/20 0.73
MAPK1 P28482 1/20 0.73
NR1H4 Q96RI1 1/20 0.62
KDM4E B2RXH2 4/20 0.56
ALDH1A1 P00352 4/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
HSP90AA1 P07900 2/20 0.56
MITF O75030 1/20 0.56
HTT P42858 1/20 0.56
CA12 O43570 2/20 0.56
CA1 P00915 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1068265 0.93 MEN1 (0.85) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL7700123 0.92 KDM4E (0.66) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL3519648 0.92 KMT2A (0.68) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL7700121 0.92 KDM4E (0.66) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL11174096 0.88 KMT2A (0.58) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL11174104 0.88 KMT2A (0.58) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL15095092 0.87 MEN1 (0.77) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL12869950 0.86 MEN1 (0.56) KMT2AMEN1MAPTLMNANPSR1
SCHEMBL935186 0.85 MEN1 (1.00) KMT2AMEN1MAPTLMNANPSR1
Benzene SCHEMBL27988126 0.85 MEN1 (1.00) KMT2AMEN1MAPTLMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2067185-A None JP disclosed
EP-2595952-B1 AGONISTS OF GPR40 CONNEXIOS LIFE SCIENCES PVT LTD (IN) 2020-11-18 EP disclosed
EP-2595952-B1 AGONISTS OF GPR40 CONNEXIOS LIFE SCIENCES PVT LTD (IN) 2020-11-18 EP disclosed
US-9278915-B2 Agonists of GPR40 CONNEXIOS LIFE SCIENCES PVT LTD (IN) 2016-03-08 US disclosed
US-9278915-B2 Agonists of GPR40 CONNEXIOS LIFE SCIENCES PVT LTD (IN) 2016-03-08 US disclosed
CN-103228622-B The agonist of GPR40 CONNEXIOS LIFE SCIENCES Pvt.,Ltd. (IN) 2016-01-20 CN disclosed
US-9128376-B2 Pattern forming method, actinic ray-sensitive or radiation-sensitive resin composition, resist film, method for manufacturing electronic device, and electronic device FUJIFILM CORPORATION (JP) 2015-09-08 US disclosed
US-20140248556-A1 PATTERN FORMING METHOD, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2014-09-04 US disclosed
US-8765967-B2 Microcapsules with UV filter activity and process for producing them DSM IP ASSETS B.V. (NE) 2014-07-01 US disclosed
US-8765967-B2 Microcapsules with UV filter activity and process for producing them DSM IP ASSETS B.V. (NE) 2014-07-01 US disclosed
EP-0141140-A1 Benzylidene malonic acid polyesters, process for their preparation and the use of such polyesters in the stabilisation of thermoplastic resins against U.V. BAYER AG (DE) 1985-05-15 EP disclosed
US-4276401-A N-Heterocyclic substituted acryloyl polymeric compounds CIBA-GEIGY CORPORATION (US) 1981-06-30 US disclosed
US-4203889-A CYCLOHEXANONE OR ACETONE OXIME WITH A UV ABSORBER AND A PHENOLIC ANTIOXIDANT AMERICAN CYANAMID COMPANY (US) 1980-05-20 US disclosed
US-4157359-A Polyurethanes stabilized against ultraviolet light and nitrogen oxide deterioration AMERICAN CYANAMID CO. (US) 1979-06-05 US disclosed
US-4130542-A ALIPHATIC ISOCYANATES AMERICAN CYANAMID COMPANY (US) 1978-12-19 US disclosed
US-4012399-A ULTRAVIOLET LIGHT ABSORBERS AND STABILIZERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1977-03-15 US disclosed
US-4000101-A POLYPROPYLENE WESTON CHEMICAL CORPORATION (US) 1976-12-28 US disclosed
US-3997464-A 1-HYDROXY-4-(P-TOLUIDINO)-9,10-ANTHRAQUINONE, A COPPER PHTHALOCYANINE TRISULFONAMIDE, UV ABSORBER AMERICAN CYANAMID COMPANY (US) 1976-12-14 US disclosed
US-3959220-A Polymer additives comprising transition metal complexes with trivalent phosphorous compounds CINCINNATI MILACRON CHEMICALS, INC. (US) 1976-05-25 US disclosed
US-3943094-A Polymers and copolymers based on alkenoyl-oxybenzylidene-malonic esters as UV-absorbers and polymers stabilized therewith BAYER AKTIENGESELLSCHAFT (DT) 1976-03-09 US disclosed