Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 2/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535555 | 0.94 | ATM (0.50) | ATMKMT2AMEN1CYP3A4APP | |
| SCHEMBL15095218 | 0.86 | NPC1 (0.43) | CYP3A4 | |
| SCHEMBL29648792 | 0.79 | KMT2A (0.49) | ATMKMT2AMEN1APPKLK5 | |
| SCHEMBL8535259 | 0.77 | KLK5 (0.42) | ATMKMT2AMEN1APPCTSD | |
| SCHEMBL29602242 | 0.74 | KMT2A (0.67) | ATMKMT2AMEN1APPKLK5 | |
| SCHEMBL8130179 | 0.74 | KMT2A (0.67) | ATMKMT2AMEN1APPKLK5 | |
| SCHEMBL6447422 | 0.73 | ATM (0.56) | ATMKMT2AMEN1APPKLK5 | |
| SCHEMBL8542012 | 0.73 | CYP3A4 (0.59) | ATMKMT2AMEN1CYP3A4APP | |
| SCHEMBL29484184 | 0.73 | KMT2A (0.66) | ATMKMT2AMEN1APPCTSD | |
| SCHEMBL8531207 | 0.73 | KLK5 (0.61) | CTSDKLK5PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481571-B2 | Anti-coronavirus compounds | ACADEMIA SINICA (TW) | 2013-07-09 | — | — | US | disclosed |
| US-8481571-B2 | Anti-coronavirus compounds | ACADEMIA SINICA (TW) | 2013-07-09 | — | — | US | disclosed |