SCHEMBL1509532

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12834192	0.94	MAPK14 (0.47)	CARM1MAPK14HDAC3HDAC1HDAC2
	SCHEMBL12833757	0.92	SMN1; SMN2 (0.45)	CARM1EGLN1MAPK14HDAC3HDAC1
	SCHEMBL12833445	0.92	CARM1 (0.47)	CARM1EGLN1MAPK14HDAC3HDAC1
	SCHEMBL12833745	0.92	SMN1; SMN2 (0.47)	CARM1MAPK14HDAC3HDAC1HDAC2
	SCHEMBL12834171	0.90	ALDH1A1 (0.46)	CARM1MAPK14
	SCHEMBL12833953	0.89	TBK1 (0.46)	CARM1GSK3BROCK2ROCK1TBK1
	SCHEMBL12833424	0.89	PDE10A (0.44)	CARM1MAPK14HDAC3HDAC1HDAC2
	SCHEMBL14090932	0.89	GSK3B (0.45)	CARM1EGLN1HDAC3HDAC1HDAC2
	SCHEMBL12834036	0.89	GSK3B (0.53)	CARM1EGLN1MAPK14HDAC3HDAC1
	SCHEMBL12833813	0.89	DRD4 (0.52)	CARM1MAPK14GSK3BROCK2ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.