Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO2A1 | Q92959 | 3/20 | 0.64 |
| ▸ | PTGFR | P43088 | 9/20 | 0.55 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.55 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18656591 | 0.84 | SLCO2A1 (0.70) | SLCO2A1PTGFRPTGER3TBXA2RALDH1A1 | |
| SCHEMBL3364894 | 0.82 | PTGFR (0.71) | SLCO2A1PTGFRPTGER3TBXA2RALDH1A1 | |
| SCHEMBL11846521 | 0.82 | PTGFR (0.71) | SLCO2A1PTGFRPTGER3TBXA2RALDH1A1 | |
| SCHEMBL1747671 | 0.82 | PTGFR (0.71) | SLCO2A1PTGFRPTGER3TBXA2RALDH1A1 | |
| SCHEMBL13061506 | 0.81 | PTGFR (0.73) | SLCO2A1PTGFRPTGER3TBXA2RALDH1A1 | |
| SCHEMBL11373483 | 0.79 | ALDH1A1 (0.58) | SLCO2A1PTGFRPTGER3TBXA2RALDH1A1 | |
| SCHEMBL8901815 | 0.79 | TBXA2R (0.60) | SLCO2A1PTGFRPTGER3TBXA2RALDH1A1 | |
| SCHEMBL8901811 | 0.79 | TBXA2R (0.60) | SLCO2A1PTGFRPTGER3TBXA2RALDH1A1 | |
| Latanoprost Acid SCHEMBL12087458 | 0.79 | SLCO2A1 (1.00) | SLCO2A1PTGFRPTGER3PTGER1MEN1 | |
| Latanoprost Acid SCHEMBL1313162 | 0.79 | SLCO2A1 (1.00) | SLCO2A1PTGFRPTGER3PTGER1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481758-B2 | Process for the production of prostaglandins and prostaglandin analogs | SANDOZ AG (CH) | 2013-07-09 | — | — | US | disclosed |