Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO2A1 | Q92959 | 3/20 | 0.70 |
| ▸ | PTGFR | P43088 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.60 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.60 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.60 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.60 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364894 | 0.93 | PTGFR (0.71) | SLCO2A1PTGFRALDH1A1TBXA2RLMNA | |
| SCHEMBL11846521 | 0.93 | PTGFR (0.71) | SLCO2A1PTGFRALDH1A1TBXA2RLMNA | |
| SCHEMBL1747671 | 0.93 | PTGFR (0.71) | SLCO2A1PTGFRALDH1A1TBXA2RLMNA | |
| SCHEMBL13061506 | 0.92 | PTGFR (0.73) | SLCO2A1PTGFRALDH1A1TBXA2RLMNA | |
| SCHEMBL14370090 | 0.87 | SLCO2A1 (0.53) | SLCO2A1PTGFRALDH1A1TBXA2RLMNA | |
| SCHEMBL15095503 | 0.84 | SLCO2A1 (0.64) | SLCO2A1PTGFRALDH1A1TBXA2RLMNA | |
| SCHEMBL8901815 | 0.84 | TBXA2R (0.60) | SLCO2A1PTGFRALDH1A1TBXA2RLMNA | |
| SCHEMBL8901811 | 0.84 | TBXA2R (0.60) | SLCO2A1PTGFRALDH1A1TBXA2RLMNA | |
| SCHEMBL11373483 | 0.83 | ALDH1A1 (0.58) | SLCO2A1PTGFRALDH1A1TBXA2RLMNA | |
| SCHEMBL19556617 | 0.83 | PTGFR (0.60) | SLCO2A1PTGFRALDH1A1TBXA2RLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9808531-B2 | Compounds and compositions for the treatment of ocular disorders | Graybug Vision, Inc. (US) | 2017-11-07 | — | — | US | disclosed |
| US-20170080092-A1 | Compounds And Compositions for the Treatment of Ocular Disorders | Graybug Vision, Inc. (US) | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170080092-A1 | Compounds And Compositions for the Treatment of Ocular Disorders | PTGIR, PTGIS, CA2 | SLCO2A1 1556/4885PTGFR 24/4885ALDH1A1 1010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.