Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 2/20 | 0.39 |
| ▸ | MMP12 | P39900 | 2/20 | 0.39 |
| ▸ | HRAS | P01112 | 1/20 | 0.37 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.36 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.36 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612285 | 0.92 | POLB (0.41) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL16377091 | 0.77 | ALDH1A1 (0.41) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL11438817 | 0.75 | USP2 (0.53) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL17975737 | 0.75 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL21754836 | 0.75 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL18474917 | 0.75 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL19619197 | 0.75 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL21754881 | 0.75 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL12222446 | 0.75 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL12300564 | 0.75 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481713-B2 | Preparation of alkyl-substituted 2-deoxy-2-fluoro-D-ribofuranosyl pyrimidines and purines and their derivatives | GILEAD PHARMASSET LLC (US) | 2013-07-09 | — | — | US | disclosed |