Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.40 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.40 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.40 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAPDH | P04406 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HRAS | P01112 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15095554 | 0.92 | USP2 (0.45) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL21059437 | 0.77 | LGALS9 (0.55) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL16377091 | 0.76 | ALDH1A1 (0.41) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL17612310 | 0.76 | POLB (0.50) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL21082629 | 0.76 | POLB (0.50) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL13871575 | 0.76 | POLB (0.50) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL14209005 | 0.76 | POLB (0.50) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL14356282 | 0.75 | LGALS9 (0.54) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL13184475 | 0.75 | PTPN1 (0.48) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL13496124 | 0.75 | PTPN1 (0.48) | POLBMEN1USP2KMT2ALGALS9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290533-B2 | β-L-2′-deoxy-nucleosides for the treatment of hepatitis B | NOVARTIS AG (CH) | 2016-03-22 | — | — | US | disclosed |