Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | ESR1 | P03372 | 4/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.63 |
| ▸ | SHBG | P04278 | 3/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.63 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.63 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980770 | 0.92 | HSD17B10 (0.64) | HSD17B10LMNAESR1ESR2TSHR | |
| SCHEMBL547773 | 0.91 | HSD17B10 (0.66) | HSD17B10LMNAESR1ESR2TSHR | |
| SCHEMBL8459399 | 0.91 | HSD17B10 (0.66) | HSD17B10LMNAESR1ESR2TSHR | |
| SCHEMBL7621594 | 0.89 | HSD17B10 (0.60) | HSD17B10LMNAESR1ESR2TSHR | |
| SCHEMBL10711260 | 0.87 | HSD17B10 (0.58) | HSD17B10LMNAESR1ESR2TSHR | |
| SCHEMBL29027144 | 0.87 | LMNA (0.61) | HSD17B10LMNAESR1ESR2TSHR | |
| SCHEMBL27462283 | 0.87 | ESR1 (0.58) | HSD17B10LMNAESR1ESR2TSHR | |
| SCHEMBL301391 | 0.87 | LMNA (0.61) | HSD17B10LMNAESR1ESR2TSHR | |
| SCHEMBL16369629 | 0.87 | HSD17B10 (0.58) | HSD17B10LMNAESR1ESR2TSHR | |
| SCHEMBL27597807 | 0.87 | HSD17B10 (0.58) | HSD17B10LMNAESR1ESR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295041-A2 | HRT formulations | Novo Nordisk Femcare AG (CH) | 2011-03-16 | — | — | EP | disclosed |