Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.66 |
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | SHBG | P04278 | 3/20 | 0.66 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | BLM | P54132 | 2/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | THPO | P40225 | 1/20 | 0.66 |
| ▸ | GMNN | O75496 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459399 | 1.00 | HSD17B10 (0.66) | HSD17B10LMNACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL980770 | 0.92 | HSD17B10 (0.64) | HSD17B10LMNACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL1509625 | 0.91 | HSD17B10 (0.63) | HSD17B10LMNACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL7621594 | 0.89 | HSD17B10 (0.60) | HSD17B10LMNACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL11875499 | 0.89 | HSD17B10 (0.67) | HSD17B10LMNACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL11577800 | 0.89 | HSD17B10 (0.67) | HSD17B10LMNACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL301391 | 0.87 | LMNA (0.61) | HSD17B10LMNACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL10711260 | 0.87 | HSD17B10 (0.58) | HSD17B10LMNACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL29027144 | 0.87 | LMNA (0.61) | HSD17B10LMNACYP19A1CYP1A2CYP3A4 | |
| SCHEMBL16369629 | 0.87 | HSD17B10 (0.58) | HSD17B10LMNACYP19A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230003721-A1 | MITOTHERAPEUTICS FOR THE TREATMENT OF BRAIN DISORDERS | THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2023-01-05 | — | — | US | claimed |
| CN-113480588-A | Preparation method of estradiol mesilate | 南雄阳普医疗科技有限公司 | 2021-10-08 | — | — | CN | claimed |
| EP-0340247-B1 | NEW PROCESS FOR THE ANTIPODAL SEPARATION OF BICYCLO 3.3.0]OCTANE-3,7-DION-2-CARBOXYLIC ACID ESTERS AND THEIR 7-MONOCETALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-04-28 | — | — | EP | claimed |
| US-5093490-A | Process for optical resolution of bicyclo[3.3.0]octane-3,7-dione-2 carboxylic acid esters and their 7-monoketals | SCHERING AKTIENGESELLSCHAFT | 1992-03-03 | — | — | US | claimed |
| CN-88101278-A | Optical resolution bicyclo (3,3,0) suffering-3, the novel method of 7-diketone-2-carboxylicesters and 7-one ketal thereof | — | 1988-09-28 | — | — | CN | claimed |
| US-20230056311-A1 | METHOD FOR IMPROVING PRODUCTION OF STREPTOMYCES POLYKETIDE COMPOUNDS | INSTITUTE OF MICROBIOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2023-02-23 | — | — | US | disclosed |
| US-20230003721-A1 | MITOTHERAPEUTICS FOR THE TREATMENT OF BRAIN DISORDERS | THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2023-01-05 | — | — | US | disclosed |
| CN-113480588-A | Preparation method of estradiol mesilate | 南雄阳普医疗科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-113480588-A | Preparation method of estradiol mesilate | 南雄阳普医疗科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| US-20140378426-A1 | Methods and compositions for enhancing visual function | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-12-25 | — | — | US | disclosed |
| US-8793078-B2 | Method for predicting activation energy using atomic fingerprint descriptor or atomic descriptor | BIOINFORMATICS & MOLECULAR DESIGN RESEARCH CENTER (KR) | 2014-07-29 | — | — | US | disclosed |
| US-20130123523-A1 | METHODS FOR THE PREPARATION OF ETONOGESTREL AND DESOGESTREL | EVESTRA, INC. | 2013-05-16 | — | — | US | disclosed |
| WO-2003002058-A2 | BONE ANABOLIC COMPOUNDS AND METHODS OF USE | ANABONIX, INC. (US) | 2003-01-09 | — | — | WO | disclosed |
| WO-2002102390-A1 | ENHANCED DRUG DELIVERY IN TRANSDERMAL SYSTEMS | NOVEN PHARMACEUTICALS, INC. (US) | 2002-12-27 | — | — | WO | disclosed |
| US-5962445-A | Treatment of asthma and airway diseases | AMRAD OPERATIONS PTY LTD. (AU) | 1999-10-05 | — | — | US | disclosed |
| US-5760255-A | Process for the conversion of hydroxyl groups into the corresponding fluorine compounds | BAYER AG (DE) | 1998-06-02 | — | — | US | disclosed |
| US-5093490-A | Process for optical resolution of bicyclo[3.3.0]octane-3,7-dione-2 carboxylic acid esters and their 7-monoketals | SCHERING AKTIENGESELLSCHAFT | 1992-03-03 | — | — | US | disclosed |
| CN-88101278-A | Optical resolution bicyclo (3,3,0) suffering-3, the novel method of 7-diketone-2-carboxylicesters and 7-one ketal thereof | — | 1988-09-28 | — | — | CN | disclosed |
| US-4050998-A | Electrolytic reduction of aromatic steroids | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3959322-A | Synthesis of 13-alkyl-gon-4-ones | Smith, Herchel (US) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123523-A1 | METHODS FOR THE PREPARATION OF ETONOGESTREL AND DESOGESTREL | GNRHR, CYP19A1, HSD17B11 | HSD17B10 182/4885LMNA 800/4885CYP19A1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.