Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107548 | 0.92 | CYP2C19 (0.46) | TDP1TSHRALDH1A1CYP2C19CA2 | |
| SCHEMBL13283544 | 0.88 | — | — | |
| SCHEMBL14400112 | 0.88 | — | — | |
| SCHEMBL104058 | 0.88 | — | — | |
| SCHEMBL11405886 | 0.87 | TSHR (0.44) | TDP1TSHRCYP2C19CA2CA1 | |
| SCHEMBL21478225 | 0.85 | CA1 (0.30) | CA2CA1CA7CA14ELANE | |
| SCHEMBL3237663 | 0.84 | — | — | |
| SCHEMBL12820604 | 0.84 | — | — | |
| SCHEMBL11460256 | 0.84 | — | — | |
| Formaldehyde SCHEMBL2638163 | 0.84 | TDP1 (0.43) | TDP1TSHRALDH1A1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110402288-A | It is formed for pretreated higher-pressure region | SWEETWATER ENERGY INC | 2019-11-01 | — | — | CN | disclosed |
| CN-107208120-A | Rapid pretreatment | 斯威特沃特能源公司 | 2017-09-26 | — | — | CN | disclosed |
| US-9062047-B2 | Crystalline form of pyrimido[6,1-A] isoquinolin-4-one compound | VERONA PHARMA PLC (GB) | 2015-06-23 | — | — | US | disclosed |
| CN-104428421-A | Process for using tobacco | KIND CONSUMER LTD | 2015-03-18 | — | — | CN | disclosed |
| US-20130225616-A1 | CRYSTALLINE FORM OF PYRIMIDIO[6,1-A] ISOQUINOLIN-4-ONE COMPOUND | VERONA PHARMA PLC (CA) | 2013-08-29 | — | — | US | disclosed |
| WO-2013037133-A1 | PROCESS FOR PREPARING METHACRYLIC ACID AND/OR ALKYL METHACRYLATES | EVONIK ROEHM GMBH (DE) | 2013-03-21 | — | — | WO | disclosed |
| EP-1160329-B1 | An enzyme reaction method and a method for enzymatically producing an optically active cyanohydrin | NIPPON CATALYTIC CHEM IND (JP) | 2011-04-06 | — | — | EP | disclosed |
| EP-2295592-A1 | An enzyme reaction method and a method for enzymatically producing an optically active cyanohydrin | Nippon Shokubai Co., Ltd. (JP) | 2011-03-16 | — | — | EP | disclosed |
| US-20070149727-A1 | Moisture-curable resin composition | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2007-06-28 | — | — | US | disclosed |
| US-5174916-A | Lubricant additive composition containing nonionic fluorochemical polymer and method of using same | OSGOOD GORDON (US) | 1992-12-29 | — | — | US | disclosed |
| US-4824925-A | KETOXIME-BLOCKED M-XYLYLENE DIISOCYANATE | PPG INDUSTRIES, INC. (US) | 1989-04-25 | — | — | US | disclosed |
| US-4259305-A | PRECIPITATION OF HIGHER PHOSPHONITRILIC CHLORIDES BY CONTACTING WITH A KETONE | ETHYL CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |
| US-4164511-A | Manufacture of N-arylglycinonitriles | BASF AKTIENGESELLSCHAFT (DE) | 1979-08-14 | — | — | US | disclosed |
| US-4134889-A | Manufacture of glycinonitriles | BASF AKTIENGESELLSCHAFT (DE) | 1979-01-16 | — | — | US | disclosed |
| US-4097521-A | Manufacture of amidosulfonic acids | BASF AKTIENGESELLSCHAFT (DT) | 1978-06-27 | — | — | US | disclosed |
| US-4047959-A | TEXTILE FIRE RETARDANT | PENNWALT CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4042587-A | PESTICIDES | BASF AKTIENGESELLSCHAFT (DT) | 1977-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225616-A1 | CRYSTALLINE FORM OF PYRIMIDIO[6,1-A] ISOQUINOLIN-4-ONE COMPOUND | NUDT1, PNP, UMPS | TDP1 1648/4885TSHR 4207/4885ALDH1A1 479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.