SCHEMBL1509714

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16619212	1.00	CETP (0.37)	CETPADRB3ADRB2KCNH2KDM4E
	SCHEMBL9933316	1.00	CETP (0.37)	CETPADRB3ADRB2KCNH2KDM4E
	SCHEMBL1509715	1.00	CETP (0.37)	CETPADRB3ADRB2KCNH2KDM4E
	SCHEMBL21278608	0.90	KDM4E (0.40)	CETPADRB3ADRB2KCNH2KDM4E
	SCHEMBL909100	0.90	CETP (0.37)	CETPKDM4EPKMNR1H2NR1H3
	SCHEMBL18017373	0.90	GAA (0.40)	CETPADRB3KDM4EPKMNR1H2
	SCHEMBL18017416	0.90	GAA (0.40)	CETPADRB3KDM4EPKMNR1H2
	SCHEMBL908049	0.90	CETP (0.37)	CETPKDM4EPKMNR1H2NR1H3
	SCHEMBL1198624	0.90	CETP (0.37)	CETPKDM4EPKMNR1H2NR1H3
	SCHEMBL16620129	0.90	PDE5A (0.38)	CETPNR1H2NR1H3GPR119PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.