SCHEMBL15097476

SCHEMBL15097476

COSc1ccc(F)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.39
NFE2L2 Q16236 3/20 0.37
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
NQO2 P16083 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
MAPK1 P28482 1/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
PTGS1 P23219 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7183452 0.78 CA1 (0.36) ACHEALDH1A1MAPTCA1CA2
SCHEMBL14015311 0.77 CA1 (0.33) ACHENFE2L2ALDH1A1KDM4EMAPT
SCHEMBL8265860 0.76 ACHE (0.44) ACHEALDH1A1MAPTHPGDCA1
SCHEMBL15097492 0.76 CYP1A1 (0.45) ALDH1A1CYP1A2MAOA
SCHEMBL14043353 0.74
SCHEMBL14033348 0.74 ORAI1 (0.35) ACHEALDH1A1KDM4EMAPTHPGD
SCHEMBL2303866 0.74
SCHEMBL22631937 0.74 CYP2A6 (0.42) ALDH1A1MAPTHPGDRAB9AMAPK1
SCHEMBL2303871 0.74 NR1H2 (0.50) ACHEALDH1A1KDM4EMAPTHPGD
SCHEMBL2472483 0.74 CA1 (0.58) ACHEALDH1A1KDM4EMAPTCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130177851-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-11 US disclosed