SCHEMBL7183452

SCHEMBL7183452

Fc1ccc(SOSc2ccc(F)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
ACHE P22303 1/20 0.36
IDO1 P14902 5/20 0.33
AGXT P21549 2/20 0.33
TDO2 P48775 2/20 0.33
FBP1 P09467 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
ORAI1 Q96D31 1/20 0.32
ORAI2 Q96SN7 1/20 0.32
ORAI3 Q9BRQ5 1/20 0.32
TRPV6 Q9H1D0 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
LOXL2 Q9Y4K0 1/20 0.32
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15097476 0.78 ACHE (0.39) CA1CA2CA7CA9ACHE
SCHEMBL14033348 0.78 ORAI1 (0.35) CA1CA2CA7CA9ACHE
SCHEMBL2734944 0.74 ORAI1 (0.32) CA1CA2CA7CA9ACHE
SCHEMBL12155241 0.74 IDO1 (0.38) CA1CA2CA7CA9ACHE
SCHEMBL27929528 0.73
SCHEMBL576260 0.71 MEN1 (0.48) CA1CA2CA7CA9ACHE
SCHEMBL223757 0.71 FBP1 (0.52) CA1CA2CA7CA9ACHE
SCHEMBL14015311 0.71 CA1 (0.33) CA1CA2CA7CA9ACHE
SCHEMBL27481650 0.71 IDO1 (0.36) IDO1
SCHEMBL27634040 0.71 LMNA (0.47) IDO1AGXTFBP1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110483349-B Preparation method of alkyl thioether 中国科学院兰州化学物理研究所 2021-01-12 CN disclosed
CN-110483349-A A kind of preparation method of alkyl thioether LANZHOU INST CHEMICAL PHYSICS CAS 2019-11-22 CN disclosed
CN-110156646-A A method of synthesis fluoroalkyl or difluoromethyl sulfur-bearing (selenium) compound 台州学院 2019-08-23 CN disclosed
CN-108091826-A Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same 三菱化学株式会社 2018-05-29 CN disclosed
CN-107188839-A A kind of sulfur-containing compound and preparation method thereof 台州学院 2017-09-22 CN disclosed
CN-106848406-A Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same 三菱化学株式会社 2017-06-13 CN disclosed
CN-104725172-B A kind of synthetic method of aryl thioethers class compound 华东师范大学 2017-03-01 CN disclosed
CN-104045589-B A kind of arylalkyl thioethers compound and synthetic method thereof 华东师范大学 2016-08-24 CN disclosed
CN-102569893-B Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same MITSUBISHI CHEMICAL CORP. (JP) 2016-05-11 CN disclosed
CN-103259044-B Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEMICAL CORP. (JP) 2016-02-10 CN disclosed
CN-102569893-A Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same MITSUBISHI CHEM CORP 2012-07-11 CN disclosed
CN-102544585-A Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same MITSUBISHI CHEM CORP JP 2012-07-04 CN disclosed
CN-101432923-B Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEM CORP 2012-04-18 CN disclosed
CN-102262250-A Optical film 2011-11-30 CN disclosed
CN-102097654-A Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEM CORP 2011-06-15 CN disclosed
CN-101652894-A Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same MITSUBISHI CHEM CORP JP 2010-02-17 CN disclosed
CN-101432923-A Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEM CORP (JP) 2009-05-13 CN disclosed
US-6583299-B1 Matrix metalloprotease inhibitors; nonsuppression of tumor necrosis factor production G.D. SEARLE & CO. 2003-06-24 US disclosed
EP-1178959-A1 ALPHA-AMINO-BETA-SULFONYL HYDROXAMIC ACID COMPOUNDS G.D. SEARLE & CO. (US) 2002-02-13 EP disclosed
WO-2000071514-A1 α-AMINO-β-SULFONYL HYDROXAMIC ACID COMPOUNDS G.D. SEARLE & CO. (US) 2000-11-30 WO disclosed