SCHEMBL15097477

SCHEMBL15097477

COSc1ccc(C(C)(C)C)c(C(F)(F)F)c1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AR P10275 9/20 0.38
HPN P05981 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
SIRT5 Q9NXA8 1/20 0.32
NOTUM Q6P988 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15097489 0.80 KIF11 (0.33)
SCHEMBL19117428 0.78 AR (0.40) ARHPNMAPTALOX15SIRT5
SCHEMBL15097112 0.78 AR (0.33) ARHPNMAPTALOX15SIRT5
SCHEMBL15097482 0.76 FABP4 (0.33) NOTUM
SCHEMBL15097478 0.76 NOTUM (0.39) ARNOTUM
SCHEMBL15097504 0.72 PRKDC (0.33)
SCHEMBL15097491 0.72 MAOB (0.40) ARMAPT
SCHEMBL8225493 0.72 CA1 (0.48) AR
SCHEMBL15097613 0.70 AR (0.36) AR
SCHEMBL6371416 0.69 SMN1; SMN2 (0.43) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130177851-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-11 US disclosed