SCHEMBL15097515

SCHEMBL15097515

CCCCCCCCCCCCc1c(Br)cc(SOC)cc1Br

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 9/20 0.40
GPR35 Q9HC97 4/20 0.35
CYP19A1 P11511 1/20 0.34
PTGS2 P35354 6/20 0.33
PTGS1 P23219 1/20 0.33
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15097486 0.80 ALOX5 (0.43) ALOX5CYP19A1PTGS2
SCHEMBL15097500 0.80 ALOX5 (0.41) ALOX5PTGS2
SCHEMBL15097806 0.76 ALOX5 (0.37) ALOX5CYP19A1THRB
SCHEMBL15097808 0.76 ALOX5 (0.37) ALOX5CYP19A1PTGS2
SCHEMBL15097496 0.76 AR (0.40) ALOX5
SCHEMBL8359711 0.74 PTGS2 (0.53) PTGS2PTGS1THRATHRB
SCHEMBL14814601 0.74 PTGS2 (0.53) PTGS2PTGS1THRATHRB
SCHEMBL15097502 0.74 ESR1 (0.39) ALOX5PTGS2
SCHEMBL21097245 0.73 PTGS2 (0.57) ALOX5PTGS2PTGS1
SCHEMBL15097494 0.70 ESR1 (0.53) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130177851-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-11 US disclosed