Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1509768 | 0.76 | ALDH1A1 (0.45) | HPGDALDH1A1GAAHSD17B10KDM4E | |
| SCHEMBL969756 | 0.72 | RAB9A (0.54) | HPGDALDH1A1GAAHSD17B10KDM4E | |
| SCHEMBL969831 | 0.71 | RAB9A (0.53) | HPGDALDH1A1GAAHSD17B10KDM4E | |
| SCHEMBL970575 | 0.71 | RAB9A (0.53) | HPGDALDH1A1GAAHSD17B10KDM4E | |
| SCHEMBL2712798 | 0.69 | ALDH1A1 (0.41) | HPGDALDH1A1GAAHSD17B10KDM4E | |
| SCHEMBL972064 | 0.68 | KDM4E (0.48) | HPGDALDH1A1GAAHSD17B10KDM4E | |
| SCHEMBL13174220 | 0.68 | ALDH1A1 (0.52) | HPGDALDH1A1GAAHSD17B10KDM4E | |
| SCHEMBL970079 | 0.67 | ALDH1A1 (0.49) | HPGDALDH1A1GAAHSD17B10KDM4E | |
| SCHEMBL3095284 | 0.67 | IKBKB (0.56) | HPGDALDH1A1GAAHSD17B10KDM4E | |
| SCHEMBL3242500 | 0.66 | IKBKB (0.50) | HPGDALDH1A1GAAHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298766-A1 | Substituted pyridine derivatives | H. Lundbeck A/S (DK) | 2011-03-23 | — | — | EP | disclosed |