SCHEMBL15099561

SCHEMBL15099561

CCc1ccc(-c2ccc(Cl)nc2Cl)cc1C1=C(O)[C@H]2CCC(C2)C1=O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
STK10 O94804 1/20 0.31
SLK Q9H2G2 1/20 0.31
GPR119 Q8TDV5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18971258 1.00 STK10 (0.31) STK10SLKGPR119
SCHEMBL12116031 1.00 STK10 (0.31) STK10SLKGPR119
SCHEMBL18971259 1.00 STK10 (0.31) STK10SLKGPR119
SCHEMBL12116028 0.91 METAP2 (0.36)
SCHEMBL18971354 0.91 METAP2 (0.36)
SCHEMBL15099521 0.85 PIK3CA (0.35)
SCHEMBL18971179 0.85 PIK3CA (0.35)
SCHEMBL12116025 0.85 PIK3CA (0.35)
SCHEMBL430205 0.84 STK10 (0.32) STK10SLK
SCHEMBL12116074 0.83 CTSK (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2387311-B1 BICYCLIC 1,3-DIONES AND THEIR USE AS INSECITICIDES, ACARICIDES AND/OR FUNGICIDES BAYER CROPSCIENCE AG (DE) 2013-07-10 EP disclosed