Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3301175 | 1.00 | CASP1 (0.33) | CASP1 | |
| SCHEMBL20477493 | 1.00 | CASP1 (0.33) | CASP1 | |
| SCHEMBL3301171 | 1.00 | CASP1 (0.33) | CASP1 | |
| SCHEMBL882267 | 0.95 | CASP1 (0.33) | CASP1 | |
| SCHEMBL882265 | 0.95 | CASP1 (0.33) | CASP1 | |
| SCHEMBL15093242 | 0.89 | ALDH1A1 (0.33) | CASP1 | |
| SCHEMBL881988 | 0.89 | ALDH1A1 (0.33) | CASP1 | |
| SCHEMBL14979844 | 0.85 | CASP1 (0.33) | CASP1 | |
| SCHEMBL14979850 | 0.85 | CASP1 (0.33) | CASP1 | |
| SCHEMBL14979934 | 0.84 | ALDH1A1 (0.33) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130178413-A1 | HCV NS3 PROTEASE INHIBITORS | MSD ITALIA SRL (IT) | 2013-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130178413-A1 | HCV NS3 PROTEASE INHIBITORS | HAVCR2, CTSC, GTF3C3 | CASP1 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.