Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15107057 | 0.88 | MEN1 (0.53) | PTGDR2MEN1KMT2AAGTR1HTT | |
| SCHEMBL14277068 | 0.78 | MAPT (0.51) | PTGDR2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15106962 | 0.76 | MRGPRX4 (0.54) | PTGDR2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4595546 | 0.75 | PTGDR2 (0.68) | PTGDR2MAPTCYP2C9 | |
| SCHEMBL1371655 | 0.74 | PTGDR2 (1.00) | PTGDR2CYP2C9 | |
| SCHEMBL2495570 | 0.74 | ALDH1A1 (0.52) | PTGDR2MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL14277044 | 0.74 | PTGDR2 (0.52) | PTGDR2MAPTALDH1A1LMNAMRGPRX4 | |
| SCHEMBL4574442 | 0.74 | NPC1 (0.56) | PTGDR2MAPTALDH1A1LMNARAB9A | |
| SCHEMBL1853203 | 0.73 | PTGDR2 (0.51) | PTGDR2MAPTMRGPRX4CYP2C9 | |
| SCHEMBL6213275 | 0.71 | NPC1 (0.47) | PTGDR2RAB9AMRGPRX4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486996-B2 | Aroylfuranes and aroylthiophenes | BASILEA PHARMACEUTICA AG (CH) | 2013-07-16 | — | — | US | disclosed |