Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.32 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15123732 | 1.00 | ABCG2 (0.34) | ABCG2ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL3236976 | 0.83 | SMN1; SMN2 (0.46) | ALDH1A1KMT2AHTTPKMMEN1 | |
| SCHEMBL3236984 | 0.83 | SMN1; SMN2 (0.46) | ALDH1A1KMT2AHTTPKMMEN1 | |
| SCHEMBL15123922 | 0.80 | PLK1 (0.46) | ABCG2ALDH1A1MAPTRAB9APKM | |
| SCHEMBL15123920 | 0.80 | PLK1 (0.46) | ABCG2ALDH1A1MAPTRAB9APKM | |
| SCHEMBL3238448 | 0.78 | ALDH1A1 (0.46) | ABCG2ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL3238427 | 0.78 | ALDH1A1 (0.46) | ABCG2ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL3230021 | 0.73 | CYP1A1 (0.48) | ABCG2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3240679 | 0.73 | ABCG2 (0.44) | ABCG2KMT2AMEN1TUBB4ATUBB | |
| SCHEMBL3240659 | 0.73 | ABCG2 (0.44) | ABCG2KMT2AMEN1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582675-B1 | COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS | CHANGZHOU LE SUN PHARMACEUTICALS LTD (CN) | 2016-06-08 | — | — | EP | disclosed |
| US-8829003-B2 | Compounds for treating proliferative disorders | CHANGZHOU LE SUN PHARMACEUTICALS LIMITED (CN) | 2014-09-09 | — | — | US | disclosed |
| US-20130190325-A1 | COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS | ITEK VENTURES PTY LTD (AU) | 2013-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190325-A1 | COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS | JAK3, CDK3, PHKA1 | ABCG2 829/4885ALDH1A1 4420/4885MAPT 4628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.