Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.54 |
| ▸ | FOS | P01100 | 1/20 | 0.54 |
| ▸ | JUN | P05412 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318820 | 0.86 | MAOB (0.62) | MAOBFOSJUNBCHEALOX5 | |
| SCHEMBL6320363 | 0.86 | MAOB (0.62) | MAOBFOSJUNBCHEALOX5 | |
| SCHEMBL5446308 | 0.83 | MAOB (0.62) | MAOBFOSJUNBCHEALOX5 | |
| SCHEMBL7934305 | 0.80 | MAOB (0.66) | MAOBFOSJUNBCHEABCG2 | |
| SCHEMBL5672863 | 0.80 | NPC1 (0.54) | MAOBBCHEALOX5PTGS1PTGS2 | |
| SCHEMBL29244511 | 0.80 | MAOB (0.66) | MAOBFOSJUNBCHEABCG2 | |
| SCHEMBL1383790 | 0.80 | MAOB (0.66) | MAOBFOSJUNBCHEABCG2 | |
| SCHEMBL27497698 | 0.80 | MAOB (0.66) | MAOBFOSJUNBCHEABCG2 | |
| SCHEMBL5425057 | 0.77 | MMP1 (0.60) | MAOBFOSJUNBCHEABCG2 | |
| SCHEMBL5425061 | 0.77 | MMP1 (0.60) | MAOBFOSJUNBCHEABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2617709-A1 | Guanidine derivatives as antiviral agents | Biotron Limited (AU) | 2013-07-24 | — | — | EP | disclosed |