Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL238094 | 0.87 | ALDH1A1 (0.47) | ALDH1A1CYP2D6MAPTHDAC3HDAC4 | |
| SCHEMBL15134355 | 0.84 | ALDH1A1 (0.36) | ALDH1A1CYP2D6 | |
| SCHEMBL10063796 | 0.84 | ALDH1A1 (0.44) | ALDH1A1CYP2D6MAPTHDAC3HDAC4 | |
| SCHEMBL12308922 | 0.84 | ALDH1A1 (0.44) | ALDH1A1CYP2D6MAPTHDAC3HDAC4 | |
| SCHEMBL866981 | 0.80 | ALDH1A1 (0.44) | ALDH1A1CYP2D6MAPTHDAC3HDAC4 | |
| SCHEMBL12222648 | 0.79 | ALDH1A1 (0.41) | ALDH1A1CYP2D6MAPT | |
| SCHEMBL12087618 | 0.79 | ALDH1A1 (0.41) | ALDH1A1CYP2D6MAPTHDAC3HDAC4 | |
| SCHEMBL17212355 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CYP2D6MAPTHDAC3HDAC4 | |
| SCHEMBL264599 | 0.78 | ALDH1A1 (0.50) | ALDH1A1CYP2D6MAPTHDAC3HDAC4 | |
| SCHEMBL12254969 | 0.78 | ALDH1A1 (0.40) | ALDH1A1CYP2D6MAPTHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802235-B2 | Drug and imaging agent delivery compositions and methods | UNIVERSITY OF KANSAS (US) | 2014-08-12 | — | — | US | disclosed |
| US-20130189519-A1 | Drug and Imaging Agent Delivery Compositions and Methods | UNIVERSITY OF KANSAS (US) | 2013-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130189519-A1 | Drug and Imaging Agent Delivery Compositions and Methods | STARD10, STARD7, CASP10 | ALDH1A1 3779/4885CYP2D6 192/4885MMP8 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.