Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | KDM6B | O15054 | 1/20 | 0.73 |
| ▸ | KDM5C | P41229 | 1/20 | 0.73 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.73 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.73 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027524 | 0.98 | KDM4E (0.70) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL515966 | 0.95 | KDM4E (0.73) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL8846311 | 0.89 | KDM4E (0.62) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL11247778 | 0.87 | KDM4E (0.59) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL10958948 | 0.87 | KDM4E (0.59) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| Succinylacetone SCHEMBL503918 | 0.84 | PHF8 (1.00) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL12568555 | 0.84 | LMNA (0.69) | LMNAKMT2AMAPTTSHRNFKB1 | |
| SCHEMBL12568558 | 0.81 | TSHR (0.71) | LMNAKMT2AMAPTTSHRNFKB1 | |
| SCHEMBL503966 | 0.81 | LMNA (0.65) | LMNAKMT2AMAPTTSHRNFKB1 | |
| SCHEMBL9244411 | 0.80 | KDM4E (0.52) | KDM4EKDM6BKDM5CEGLN1PHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013110837-A1 | HAPTENS, CONJUGATES AND ANTIBODIES FOR PYRIMETHANIL FUNGICIDE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2013-08-01 | — | — | WO | disclosed |