SCHEMBL8846311

SCHEMBL8846311

CC(=O)CC(=O)CCCCC(=O)CC(C)=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.62
KDM6B O15054 1/20 0.62
KDM5C P41229 1/20 0.62
EGLN1 Q9GZT9 1/20 0.62
PHF8 Q9UPP1 1/20 0.62
KDM2A Q9Y2K7 1/20 0.62
ALDH1A1 P00352 2/20 0.44
HAO1 Q9UJM8 1/20 0.44
PAOX Q6QHF9 3/20 0.42
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
LMNA P02545 2/20 0.36
SLC15A2 Q16348 1/20 0.36
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11247778 0.97 KDM4E (0.59) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL10958948 0.97 KDM4E (0.59) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL9244411 0.89 KDM4E (0.52) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL93486 0.89 HAO1 (0.59) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL15148024 0.89 KDM4E (0.73) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL10716506 0.89 KDM4E (0.52) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL1683265 0.88 KDM4E (0.56) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL671918 0.87 HAO1 (0.63) ALDH1A1HAO1MAPTKMT2ATDP1
SCHEMBL1121769 0.87 HAO1 (0.63) ALDH1A1HAO1MAPTKMT2ATDP1
SCHEMBL4673193 0.87 KDM4E (0.50) KDM4EKDM6BKDM5CEGLN1PHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0508857-B1 Halogenated polymeric compositions stabilized by means of a mineral additive RHONE POULENC CHIMIE (FR) 1997-06-25 EP claimed
EP-0490780-B1 Stabilized compositions of a chlorinated polymer RHONE POULENC CHIMIE (FR) 1995-06-07 EP claimed
US-5278218-A Heat resistance RHONE-POULENC CHIMIE (FR) 1994-01-11 US claimed
US-5234981-A HALOGENATED POLYMER COMPOSITIONS STABILIZED WITH THE AID OF AN INORGANIC ADDITIVE RHONE-POULENC CHIMIE (FR) 1993-08-10 US claimed
US-20160220466-A1 HAIR TREATMENT COMPOSITION LONZA LTD. (CH) 2016-08-04 US disclosed
US-20100028803-A1 SURFACE TREATING AGENT FOR RESIST PATTERN FORMATION, RESIST COMPOSITION, METHOD OF TREATING SURFACE OF RESIST PATTERN THEREWITH AND METHOD OF FORMING RESIST PATTERN FUJIFILM CORPORATION (JP) 2010-02-04 US disclosed
US-20100028803-A1 SURFACE TREATING AGENT FOR RESIST PATTERN FORMATION, RESIST COMPOSITION, METHOD OF TREATING SURFACE OF RESIST PATTERN THEREWITH AND METHOD OF FORMING RESIST PATTERN FUJIFILM CORPORATION (JP) 2010-02-04 US disclosed
US-5278218-A Heat resistance RHONE-POULENC CHIMIE (FR) 1994-01-11 US disclosed
US-5234981-A HALOGENATED POLYMER COMPOSITIONS STABILIZED WITH THE AID OF AN INORGANIC ADDITIVE RHONE-POULENC CHIMIE (FR) 1993-08-10 US disclosed
US-5200444-A Polymer matrices heat and light stabilized with novel benzophenone/1,4-dihydropyridine compounds RHONE-POULENC CHIMIE (FR) 1993-04-06 US disclosed
US-5194470-A Nonyellowing polymer compositions for heat stability RHONE-POULENC CHIMIE (FR) 1993-03-16 US disclosed
US-5143959-A Mixture of dawsonite, hydrotalcite, polysiloxane and organometallic compound; heat resistant RHONE-POULENC CHIMIE (FR) 1992-09-01 US disclosed
US-5124456-A HINDERED AMINE-SUBSTITUTED DIHYDROPYRIDINES AND HEAT/LIGHT STABILIZATION OF POLYMER SUBSTRATES THEREWITH RHONE-POULENC CHIMIE (FR) 1992-06-23 US disclosed
US-5070128-A ORGANOZINC AND ORGANOALKALINE EARTH COMPOUNDS, SODIUM BETA-DIK ETONATE AS STABILIZERS RHONE-POULENC CHIMIE (FR) 1991-12-03 US disclosed
US-5034533-A Polyesterether copolymers as stabilizers for polymers RHONE-POULENC CHIMIE (FR) 1991-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160220466-A1 HAIR TREATMENT COMPOSITION FH, ABAT, FHIT KDM4E 1017/4885KDM6B 1864/4885KDM5C 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.