Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166860 | 0.84 | ATM (0.57) | ATMALDH1A1KMT2ALMNAGLA | |
| SCHEMBL166861 | 0.82 | ALDH1A1 (0.56) | ATMALDH1A1KMT2ALMNAGLA | |
| SCHEMBL26784250 | 0.82 | ATM (0.49) | ATMALDH1A1KMT2ALMNAGLA | |
| SCHEMBL23871037 | 0.81 | ALDH1A1 (0.56) | ATMALDH1A1KMT2ALMNAGLA | |
| SCHEMBL421738 | 0.81 | ATM (0.54) | ATMALDH1A1KMT2ALMNAGLA | |
| SCHEMBL20305268 | 0.81 | ALDH1A1 (0.59) | ATMALDH1A1KMT2ALMNAGLA | |
| SCHEMBL65772 | 0.81 | ATM (0.54) | ATMALDH1A1KMT2ALMNAGLA | |
| SCHEMBL8565351 | 0.81 | ATM (0.54) | ATMALDH1A1KMT2ALMNAGLA | |
| SCHEMBL421739 | 0.81 | ATM (0.54) | ATMALDH1A1KMT2ALMNAGLA | |
| SCHEMBL5116743 | 0.81 | ATM (0.54) | ATMALDH1A1KMT2ALMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121672-B1 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | ALLERGAN INC (US) | 2014-12-10 | — | — | EP | disclosed |
| EP-2331531-B1 | THERAPEUTIC SUBSTITUTED PYRROLES | ALLERGAN INC (US) | 2013-08-07 | — | — | EP | disclosed |