Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.58 |
| ▸ | PGR | P06401 | 10/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mibolerone SCHEMBL15201510 | 0.85 | AR (0.60) | ARPGRNR3C2ABCB11CYP3A4 | |
| SCHEMBL6695302 | 0.84 | AR (0.62) | ARPGRNR3C2ABCB11CYP3A4 | |
| SCHEMBL11138065 | 0.83 | PGR (0.75) | ARPGRNR3C2ABCB11CYP3A4 | |
| SCHEMBL24476186 | 0.80 | AR (0.61) | ARPGRNR3C2ABCB11CYP3A4 | |
| SCHEMBL4208646 | 0.80 | AR (0.63) | ARPGRNR3C2ABCB11CYP3A4 | |
| SCHEMBL24476600 | 0.79 | AR (0.64) | ARPGRNR3C2ABCB11CYP3A4 | |
| Mibolerone SCHEMBL4362587 | 0.78 | AR (0.67) | ARPGRNR3C2ABCB11CYP3A4 | |
| Mibolerone SCHEMBL14275154 | 0.78 | AR (0.67) | ARPGRNR3C2ABCB11CYP3A4 | |
| Mibolerone SCHEMBL565277 | 0.78 | AR (0.67) | ARPGRNR3C2ABCB11CYP3A4 | |
| Mibolerone SCHEMBL10603681 | 0.78 | AR (0.67) | ARPGRNR3C2ABCB11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2815236-A1 | MEANS AND METHODS FOR ASSESSING AN ENDOCRINE DISEASE OR DISORDER | BASF SE (DE) | 2014-12-24 | — | — | EP | disclosed |
| WO-2013121380-A1 | MEANS AND METHODS FOR ASSESSING AN ENDOCRINE DISEASE OR DISORDER | BASF SE (DE) | 2013-08-22 | — | — | WO | disclosed |