Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011502 | 0.78 | — | — | |
| SCHEMBL6011499 | 0.78 | — | — | |
| SCHEMBL5704665 | 0.78 | — | — | |
| SCHEMBL1790667 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHRCYP2C19CYP2D6HIF1A | |
| SCHEMBL17407457 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHRCYP2C19CYP2D6HIF1A | |
| Trifluoroacetic Acid SCHEMBL2267588 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHRGGT1GRM2CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL5608598 | 0.73 | ALDH1A1 (0.42) | ALDH1A1TSHRGGT1GRM2CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL7440809 | 0.73 | ALDH1A1 (0.42) | ALDH1A1TSHRGGT1GRM2CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL5608594 | 0.73 | ALDH1A1 (0.42) | ALDH1A1TSHRGGT1GRM2CYP2C19 | |
| SCHEMBL24799610 | 0.71 | ALDH1A1 (0.40) | ALDH1A1TSHRGGT1GRM2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3431489-B1 | DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION | UNIV RAMOT (IL) | 2020-12-23 | — | — | EP | disclosed |
| EP-3431489-A1 | DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION | Ramot at Tel-Aviv University Ltd. (IL) | 2019-01-23 | — | — | EP | disclosed |
| EP-2640737-B1 | DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION | UNIV RAMOT (IL) | 2018-08-29 | — | — | EP | disclosed |
| US-9630989-B2 | Dipeptide analogs for treating conditions associated with amyloid fibril formation | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2017-04-25 | — | — | US | disclosed |
| US-20150322110-A1 | DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2015-11-12 | — | — | US | disclosed |
| US-9096645-B2 | Dipeptide analogs for treating conditions associated with amyloid fibril formation | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2015-08-04 | — | — | US | disclosed |
| US-20130225512-A1 | DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322110-A1 | DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION | IAPP, APP, APBA1 | ALDH1A1 3599/4885TSHR 2665/4885GGT1 1769/4885 |
| US-20130225512-A1 | DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION | IAPP, APP, APBA1 | ALDH1A1 3602/4885TSHR 2621/4885GGT1 1865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.