Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10687383 | 0.76 | APP (0.58) | MAOBAPPMAOALMNAL3MBTL1 | |
| SCHEMBL9507201 | 0.75 | APP (0.46) | MAOBAPPMAOALMNAL3MBTL1 | |
| SCHEMBL19297784 | 0.71 | APP (0.49) | MAOBAPPMAOALMNAL3MBTL1 | |
| SCHEMBL7029327 | 0.70 | CA1 (0.58) | MAOBAPPL3MBTL1MAPTMAPK1 | |
| SCHEMBL15211338 | 0.70 | APP (0.44) | MAOBAPPMAOALMNAL3MBTL1 | |
| SCHEMBL9507453 | 0.69 | IDO1 (0.45) | MAOBAPPMAOAMAPTIDO1 | |
| SCHEMBL26601680 | 0.69 | TP53 (0.45) | MAOBAPPMAOALMNAL3MBTL1 | |
| SCHEMBL28525316 | 0.68 | APP (0.40) | MAOBAPPMAOALMNAL3MBTL1 | |
| SCHEMBL3228582 | 0.67 | APP (0.82) | MAOBAPPMAOADAOIDO1 | |
| SCHEMBL19389471 | 0.67 | MAOB (0.60) | MAOBAPPMAOALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |