Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.82 |
| ▸ | MAOB | P27338 | 3/20 | 0.74 |
| ▸ | MAOA | P21397 | 2/20 | 0.74 |
| ▸ | DAO | P14920 | 2/20 | 0.55 |
| ▸ | IDO1 | P14902 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044221 | 0.94 | APP (0.74) | APPMAOBMAOADAOIDO1 | |
| SCHEMBL19059386 | 0.94 | APP (0.74) | APPMAOBMAOADAOIDO1 | |
| SCHEMBL12945246 | 0.91 | APP (0.70) | APPMAOBMAOADAOIDO1 | |
| SCHEMBL11044220 | 0.91 | APP (0.70) | APPMAOBMAOADAOIDO1 | |
| SCHEMBL9475495 | 0.91 | APP (0.70) | APPMAOBMAOADAOIDO1 | |
| SCHEMBL18475586 | 0.91 | APP (1.00) | APPMAOBMAOADAOIDO1 | |
| SCHEMBL2433694 | 0.90 | APP (0.69) | APPMAOBMAOAHDAC3NCOR1 | |
| SCHEMBL2272164 | 0.90 | APP (0.69) | APPMAOBMAOADAOIDO1 | |
| SCHEMBL8255854 | 0.87 | APP (0.65) | APPMAOBMAOADAOIDO1 | |
| SCHEMBL2707482 | 0.86 | MAOB (1.00) | APPMAOBMAOADAOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030787-A1 | ESTROGEN RECEPTOR LIGANDS | RADIUS HEALTH, INC. (US) | 2010-03-18 | — | — | WO | disclosed |
| WO-2010030787-A1 | ESTROGEN RECEPTOR LIGANDS | RADIUS HEALTH, INC. (US) | 2010-03-18 | — | — | WO | disclosed |
| EP-0433024-B1 | Colour recording medium containing leuco dye | FUJI PHOTO FILM CO LTD (JP) | 1994-09-21 | — | — | EP | disclosed |
| EP-0433024-A1 | Colour recording medium containing leuco dye | FUJI PHOTO FILM CO., LTD. (JP) | 1991-06-19 | — | — | EP | disclosed |