Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.40 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15211271 | 0.91 | POLB (0.47) | HDAC8ADRB2FABP3FABP4FABP5 | |
| SCHEMBL15211613 | 0.90 | ADRB2 (0.44) | HDAC8ADRB2FABP3FABP4FABP5 | |
| SCHEMBL15211259 | 0.89 | HDAC8 (0.47) | HDAC8ADRB2FABP3FABP4FABP5 | |
| SCHEMBL15211226 | 0.81 | HDAC8 (0.46) | HDAC8ADRB2FABP3FABP4FABP5 | |
| SCHEMBL15211713 | 0.81 | FABP3 (0.48) | HDAC8FABP3FABP4FABP5PTGER1 | |
| SCHEMBL17444865 | 0.81 | HDAC8 (0.47) | HDAC8ADRB2FABP3FABP4FABP5 | |
| SCHEMBL15211250 | 0.81 | MBOAT4 (0.35) | ALDH1A1POLBDUSP3PTPN5PTPN11 | |
| SCHEMBL15211619 | 0.80 | POLB (0.52) | HDAC8FABP3FABP4FABP5NR4A2 | |
| SCHEMBL15211170 | 0.80 | FABP3 (0.43) | HDAC8FABP3FABP4FABP5PTGER1 | |
| SCHEMBL17431402 | 0.80 | FABP3 (0.43) | HDAC8FABP3FABP4FABP5PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |