Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | PON1 | P27169 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876286 | 0.81 | MCL1 (0.73) | MCL1ALDH1A1HPGDPON1CA9 | |
| SCHEMBL28065506 | 0.81 | MCL1 (1.00) | MCL1ALDH1A1HPGDLMNAPON1 | |
| SCHEMBL15211418 | 0.80 | MCL1 (0.75) | MCL1ALDH1A1HPGDPON1MAOB | |
| SCHEMBL29749855 | 0.80 | MAOB (0.67) | MCL1ALDH1A1HPGDLMNACA9 | |
| SCHEMBL4383562 | 0.80 | MAOB (0.67) | MCL1ALDH1A1HPGDLMNACA9 | |
| SCHEMBL31454846 | 0.78 | ERAP1 (0.54) | MCL1ALDH1A1HPGDLMNACA9 | |
| SCHEMBL15211319 | 0.77 | MCL1 (0.66) | MCL1ALDH1A1HPGDPON1MAOB | |
| SCHEMBL31454860 | 0.75 | ALDH1A1 (0.58) | MCL1ALDH1A1HPGDLMNAMAOB | |
| SCHEMBL31454864 | 0.74 | MCL1 (0.49) | MCL1ALDH1A1HPGDLMNAMAOB | |
| SCHEMBL31454884 | 0.73 | ALDH1A1 (0.65) | MCL1ALDH1A1HPGDLMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-B1 | AROMATIC RING COMPOUND AS GHRELIN O-ACYLTRANSFERASE INHIBITOR | TAKEDA PHARMACEUTICALS CO (JP) | 2017-08-02 | — | — | EP | disclosed |
| US-9238639-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-01-19 | — | — | US | disclosed |
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| CN-104254525-A | Aromatic ring compound | TAKEDA PHARMACEUTICAL | 2014-12-31 | — | — | CN | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |