SCHEMBL152118

SCHEMBL152118

CCCCCCCc1cc[c]cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.57
ESR1 P03372 2/20 0.57
ADRA2A P08913 2/20 0.57
ADORA3 P0DMS8 2/20 0.57
TACR2 P21452 2/20 0.57
SLC6A2 P23975 2/20 0.57
SLC6A4 P31645 2/20 0.57
SLC6A3 Q01959 2/20 0.57
HSD17B10 Q99714 2/20 0.57
ALDH1A1 P00352 2/20 0.57
KDM4E B2RXH2 1/20 0.57
LMNA P02545 1/20 0.57
SHBG P04278 1/20 0.57
TP53 P04637 1/20 0.57
CYP3A4 P08684 1/20 0.57
HSPD1 P10809 1/20 0.57
ADRB3 P13945 1/20 0.57
HTR2C P28335 1/20 0.57
HSPE1 P61604 1/20 0.57
HIF1A Q16665 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258640 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL2971186 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL225807 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL173702 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL3673116 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL2962583 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL2967935 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL151724 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL1610040 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL2972399 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3033 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005686-A Halogen-free phosphorus-nitrogen flame retardant and application thereof 西华大学 2024-05-10 CN claimed
CN-115928264-B Preparation method of continuous silicon carbide fiber containing metal in near-stoichiometric ratio 湖南泽睿新材料有限公司 2024-02-20 CN claimed
CN-116102478-A Preparation method of 1, 4-dicarbonyl thiosemicarbazide compound and anti-infection application 中国医学科学院药物研究所 2023-05-12 CN claimed
US-20220393118-A1 TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF CHE, CHI MING (CN) 2022-12-08 US claimed
CN-115247000-A Novel pigment and preparation method thereof 上海百艳实业有限公司 2022-10-28 CN claimed
EP-4017936-A1 TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF Che, Chi Ming (HK) 2022-06-29 EP claimed
CN-112142909-B Resistance reducing agent and preparation method thereof 中国石油天然气股份有限公司 2022-06-03 CN claimed
CN-107963982-B Polyisocyanate composition and isocyanate polymer composition 旭化成株式会社 2021-11-12 CN claimed
WO-2021036978-A1 TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF CHE CHI MING (CN) 2021-03-04 WO claimed
EP-3784677-A1 NON-COORDINATING ANION TYPE ACTIVATORS CONTAINING CATION HAVING LARGE ALKYL GROUPS ExxonMobil Chemical Patents Inc. (US) 2021-03-03 EP claimed
US-5015402-A Catalytic formation of complexes of metal phosphorodithioates, as additives for lubricants and compounds for wear resistance THE LUBRIZOL CORPORATION (US) 1991-05-14 US claimed
US-4966913-A FOR FALL ARMYWORM AND EUROPEAN CORN BORER THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1990-10-30 US claimed
US-4942247-A SULFIDE DERIVATIVES OF NITRILES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1990-07-17 US claimed
CN-1038279-A PYRAZOLOPYRIDINE TYPE MEVALONOLACTONES NISSAN CHEMICAL IND LTD (JP) 1989-12-27 CN claimed
EP-0339358-A1 Pyrazolopyridine type mevalonolactones NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1989-11-02 EP claimed
WO-1989010365-A1 PYRAZOLOPYRIDINE TYPE MEVALONOLACTONES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1989-11-02 WO claimed
WO-1989006237-A1 BASIC METAL DIHYDROCARBYLPHOSPHORODITHIOATES THE LUBRIZOL CORPORATION (US) 1989-07-13 WO claimed
US-4638011-A CARDIOVASCULAR DISORDERS, THROMBOLYTIC DISEASE E. R. SQUIBB & SONS, INC. (US) 1987-01-20 US claimed
US-4604471-A PLASTIC STABILIZERS BASF AKTIENGESELLSCHAFT (DE) 1986-08-05 US claimed
EP-0159528-A1 Tetrahydrofuranyl substituted prostaglandin analogs E.R. Squibb & Sons, Inc. (US) 1985-10-30 EP claimed