SCHEMBL1610040

SCHEMBL1610040

CCCCCCCCCCCCCCCCCCCc1cc[c]cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.57
ESR1 P03372 2/20 0.57
ADRA2A P08913 2/20 0.57
ADORA3 P0DMS8 2/20 0.57
TACR2 P21452 2/20 0.57
SLC6A2 P23975 2/20 0.57
SLC6A4 P31645 2/20 0.57
SLC6A3 Q01959 2/20 0.57
HSD17B10 Q99714 2/20 0.57
ALDH1A1 P00352 2/20 0.57
KDM4E B2RXH2 1/20 0.57
LMNA P02545 1/20 0.57
SHBG P04278 1/20 0.57
TP53 P04637 1/20 0.57
CYP3A4 P08684 1/20 0.57
HSPD1 P10809 1/20 0.57
ADRB3 P13945 1/20 0.57
HTR2C P28335 1/20 0.57
HSPE1 P61604 1/20 0.57
HIF1A Q16665 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258640 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL2971186 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL225807 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL152118 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL173702 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL3673116 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL2962583 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL2967935 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL151724 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL2972399 1.00 PTGS2 (0.57) PTGS2ESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115947711-B Photochemical caching agent and synthesis method thereof 上海泰辉生物科技有限公司 2024-06-11 CN claimed
CN-115947711-A Photochemical buffering agent and synthesis method thereof 上海泰辉生物科技有限公司 2023-04-11 CN claimed
EP-3784677-A1 NON-COORDINATING ANION TYPE ACTIVATORS CONTAINING CATION HAVING LARGE ALKYL GROUPS ExxonMobil Chemical Patents Inc. (US) 2021-03-03 EP claimed
CN-112351987-A Non-coordinating anionic activators containing cations with large alkyl groups 埃克森美孚化学专利公司 2021-02-09 CN claimed
US-20190330139-A1 Non-Coordinating Anion Type Activators Containing Cation Having Large Alkyl Groups EXXONMOBIL CHEMICAL PATENTS INC. 2019-10-31 US claimed
CN-115947711-B Photochemical caching agent and synthesis method thereof 上海泰辉生物科技有限公司 2024-06-11 CN disclosed
EP-4222180-B1 BIS(HETEROCYCLIC-OLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-04-10 EP disclosed
CN-112351987-B Non-coordinating anionic activators containing cations having large alkyl groups 埃克森美孚化学专利公司 2024-02-02 CN disclosed
US-20230357454-A1 Methods for Delivery of Non-Aromatic Solutions to Polymerization Reactors EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-11-09 US disclosed
US-11732063-B2 Lewis base catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-22 US disclosed
EP-4222180-A1 BIS(HETEROCYCLIC-OLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF ExxonMobil Chemical Patents Inc. (US) 2023-08-09 EP disclosed
CN-116323694-A Bis (heterocyclic-alkoxide) lewis base catalysts and methods thereof 埃克森美孚化学专利公司 2023-06-23 CN disclosed
WO-2006065844-A2 PROCESS FOR PRODUCING SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed
US-6511947-B1 A mixture of a polyphenyl ether having 4-5 aromatic rings and/or its hydrocarbon substituted group with a polyphenyl thioether having 3-5 aromatic rings, an amine antioxidant, a phosphate, and an amine salt of acid phosphate TONEN GENERAL SEKIYU K.K. (JP) 2003-01-28 US disclosed
US-6251300-B1 REFRIGERATOR OIL WITH FLUOROCARBON REFRIGERANTS NIPPON MITSUBISHI OIL CORPORATION (JP) 2001-06-26 US disclosed
EP-1018538-A1 REFRIGERATOR OIL COMPOSITION AND REFRIGERATOR FLUID COMPOSITION Nippon Mitsubishi Oil Corporation (JP) 2000-07-12 EP disclosed
EP-0699742-B1 Refrigerator oil composition and fluid composition for refrigerator NIPPON OIL CO LTD (JP) 1999-05-19 EP disclosed
EP-0699742-A2 Refrigerator oil composition and fluid composition for refrigerator NIPPON OIL CO. LTD. (JP) 1996-03-06 EP disclosed
WO-1988000581-A1 PREPARATION OF CARBOXYPROPYLATED NON-IONIC SURFACTANTS GAF CORPORATION (US) 1988-01-28 WO disclosed
US-4692551-A SALT FORMATION OF ALCOHOL ETHER WITH METAL HYDROXIDE, REACTING SALT WITH A BUTYROLACTONE GAF CORPORATION (US) 1987-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11732063-B2 Lewis base catalysts and methods thereof TEC, ALOX12, ELL PTGS2 320/4885ESR1 18/4885ADRA2A 4508/4885
US-20190330139-A1 Non-Coordinating Anion Type Activators Containing Cation Having Large Alkyl Groups KCNK10, KCNK4, HCN4 PTGS2 4100/4885ESR1 996/4885ADRA2A 999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.