Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15220613 | 0.88 | BACE1 (0.32) | BACE1KCNH2NPC1MAPTNPSR1 | |
| SCHEMBL15220647 | 0.87 | NPC1 (0.31) | NPC1MAPTNPSR1 | |
| SCHEMBL15211938 | 0.85 | NPC1 (0.30) | NPC1 | |
| SCHEMBL15220642 | 0.83 | — | — | |
| SCHEMBL15220640 | 0.83 | NPC1 (0.32) | NPC1 | |
| SCHEMBL15220641 | 0.81 | — | — | |
| SCHEMBL15220646 | 0.81 | SIRT2 (0.31) | NPC1 | |
| SCHEMBL15220628 | 0.80 | DRD2 (0.31) | — | |
| SCHEMBL15220633 | 0.80 | — | — | |
| SCHEMBL15211543 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9132073-B2 | Oxidation dye precursors | HENKEL AG & CO. KGAA (DE) | 2015-09-15 | — | — | US | claimed |
| EP-2816992-A2 | NOVEL OXIDATION DYE PRECURSORS | Henkel AG & Co. KGaA (DE) | 2014-12-31 | — | — | EP | claimed |
| US-20140359951-A1 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2014-12-11 | — | — | US | claimed |
| WO-2013124363-A2 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2013-08-29 | — | — | WO | claimed |
| US-9132073-B2 | Oxidation dye precursors | HENKEL AG & CO. KGAA (DE) | 2015-09-15 | — | — | US | disclosed |
| US-9132073-B2 | Oxidation dye precursors | HENKEL AG & CO. KGAA (DE) | 2015-09-15 | — | — | US | disclosed |
| US-20140359951-A1 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2014-12-11 | — | — | US | disclosed |
| US-20140359951-A1 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2014-12-11 | — | — | US | disclosed |
| WO-2013124363-A2 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2013-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140359951-A1 | NOVEL OXIDATION DYE PRECURSORS | KRT18, COXFA4L2, CYB5R3 | BACE1 3771/4885KCNH2 1037/4885NPC1 4512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.